Culturing monocytes with IL-4, TNF-.alpha. and GM-CSF TO induce

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Method of regulating cell metabolism or physiology

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424 9371, 435375, C12N 500, A01N 6300

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058495894

ABSTRACT:
Disclosed is a method for inducing the differentiation of a monocyte into a dendritic cell, the method including the culturing of a monocyte in a medium including GM-CSF, IL-4, and TNF-.alpha..

REFERENCES:
patent: 4845653 (1989-07-01), Conrad et al.
patent: 5316920 (1994-05-01), Tedder et al.
patent: 5648219 (1997-07-01), MacKay et al.
Morse et al., "CD83 is a marker for mature dentritic cells generated from peripheral blood mononuclear cells", 37th Annual Meeting of the Americal Society of Hematology, Blood 86 (10 Suppl. 1): 323a (1995).
Zhou et al., "CD83 is a marker for mature dendritic cells generated from peripheral blood mononuclear cells", 37th Annual Metting of the American Society of Hematology, Blood 86 (10 Suppl. 1):323| (1995).
Cameron et al., Science 257:383-387 (1992).
Cameron et al., Clin. Exp. Immunol. 88:226-236 (1992).
Caux et al., Nature 360:258-261 (1992).
Caux et al., Immunology Today 16:2-4 (1995).
Clare-Salzler et al., J. Clin. Invest. 90:741-748 (1992).
Egner et al., Transplantation Proc. 24:2318 (1992).
Egner et al., Transplantation 56:945-950 (1993).
CD83 Workshop Report, Engel, P., Wagner, N. and Tedder, T.F., eds., Oxford University Press, Oxford, vol. 1, pp. 693-695 (1995).
Freudenthal et al., Proc. Natl. Acad. Sci. USA 87:7698-7702 (1990).
Grage-Griebenow et al., Eur. J. Immunol 23:3126-3135 (1993).
Inaba et al., J. Exp. Med. 175:1157-1167 (1992).
Inaba et al., J. Exp. Med. 176:1693-1702 (1992).
Inaba et al., J. Exp. Med. 178:479-488 (1993).
Inaba et al., Proc. Natl. Acad. Sci. USA 90:3038-3042 (1993).
Kabel et al., Immunobiol. 179:395-411 (1989).
Kasinrerk et al., J. Immunol 150:579-584 (1993).
Knight et al., Immunology 57:595-603 (1986).
Knight et al., J. Invest. Dermatol. Supplement 99:33S-38S (1992).
Kuntz-Crow et al., Clin. Exp. Immunol. 49:338-346 (1982).
Langhoff et al., J. Invest. Dermatol. 99:89S-94S (1992).
Langhoff et al., J. Clin. Invest. 91:2721-2726 (1993).
Levine et al., Proc. Natl. Acad. Sci. USA 89:8342-8346 (1992).
Najar et al., Eur. J. Immunol. 51:339-346 (1990).
Nestle et al., J. Immunol. 151:6535-6545 (1993).
O'Doherty et al., J. Exp. Med. 178:1067-1078 (1993).
O'Doherty et al., Immunol. 82:487-493 (1994).
Patterson et al., J. Gen. Virol. 76:1155-1163 (1995).
Peters et al., Pathobiol. 59:122-126 (1991).
Pinchuk et al., Immunity 1:317-325 (1994).
Pope et al., Cell 78:389-398 (1994).
Reid et al., Blood 76:1139-1149 (1990).
Reid et al., J. Immunol. 149:2681-2688 (1992).
Romani et al., J. Exp. Med. 180:83-93 (1994).
Ruppert et al., Immunobiology 182:449-464 (1991).
Sallusto et al., J. Exp. Med. 179:1109-1118 (1994).
Santiago-Schwarz et al., J. Leukoc. Biol. 52:274-281 (1992).
Santiago-Schwarz et al., Blood 82:3019-3028 (1993).
Steinman et al., J. Exp. Med. 157:613-627 (1983).
Steinman et al., Annu. Rev. Immunol. 9:271-296 (1991).
Stingl and Bergstresser, Immunology Today 16:330-333 (1995).
Szabolcs et al., J. Immunol. 154:5851-5861 (1995).
Thomas et al., J. Immunol. 150:821-834 (1993).
Van Voorhis et al., J. Exp. Med. 155:1172-1187 (1982).
Weissman et al., Proc. Natl. Acad. Sci. USA 92:826-830 (1995).
Wood et al., Ameri. J. Path. 141:789-795 (1992).
Xu et al., Scand. J. Immunol. 36:689-696 (1992).
Young et al., Cell. Immunol. 111:167-182 (1988).
Young et al., J. Exp. Med. 171:1315-1332 (1990).
Zhou et al., Blood 86:3295-3301 (1995).
Zhou et al., J. of Immunol. 149:735-742 (1992).
Zhou and Tedder, J. of Immunol. 154:3821-3835 (1995).
Ziegler et al., J. of Autoimmunity 5:571-579 (1992).

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