Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor
Patent
1994-10-14
1996-12-10
Marx, Irene
Chemistry: molecular biology and microbiology
Micro-organism, per se ; compositions thereof; proces of...
Bacteria or actinomycetales; media therefor
435119, 4351721, 4351722, 435 76, 435 75, 536 71, C12N 120, C12N 1500, C12P 1718
Patent
active
055830293
ABSTRACT:
Mutants of Streptomyces avermitilis lacking ability to produce glycosylated avermectins and lacking branched-chain 2-oxo acid dehydrogenase activity, method for preparation thereof, and use thereof to produce natural and non-natural avermectin aglycones useful as parasiticides.
REFERENCES:
patent: 4199569 (1980-04-01), Chabala et al.
patent: 4206205 (1980-06-01), Mrozik et al.
patent: 4285963 (1981-08-01), Arison et al.
patent: 4310519 (1982-01-01), Albers-Schonberg
patent: 4328335 (1982-05-01), Mrozik
patent: 4333925 (1982-06-01), Buhs et al.
patent: 4378353 (1983-03-01), Goegelman et al.
patent: 4423209 (1983-12-01), Mrozik
patent: 4429042 (1984-01-01), Albers-Schonberg
patent: 4831016 (1989-05-01), Mrozik
Burg, R. W. et al., Antimicrob. Agents Chemother. 15:361-367 (1979).
Chen et al., Abstr. Pap. Am. Chem. Soc. 1983, 186 Meet. MBTD 28.
Cheremisinoff et al., Biotechnology, 1985, Technomic Publ. pp. 14-15.
Daum, S. J. et al., Ann. Rev. Microbiol. 33:241-265 (1979).
Fisher & Mrozik, Macrolide Antibiotics, Academic Press (1984), Chapter 14.
Gray, P. P. et al., J. Ferm. Technol. 50:381-387 (1971).
Manual of Methods for General Microbiology, P. Gerhardt, Editor-in-Chief, American Society for Microbiology, Washington, D.C., 1981, pp. 365-370.
Martin et al., J. Bacteriol. 115:198-204 (1973).
Ruby et al., 6th Int. Symp. on Actinomycete Biology, 1985, pp. 279-280.
Schulman et al., Antimicrobial Agents and Chemotherapy, 29:620-624 (1986).
Schulman et al., Antimicrobial Agents and Chemotherapy 31:744-747 (1987).
Schulman et al., Fed. Proc. 44:931 (1985).
Schulman et al., J. Antibiot. 38(11), 1494-1498 (1985).
Schulman, M. D. et al., J. Antibiotics 34:541-549 (1986).
Tabor et al., J. Bact. 128:485-486 (1976).
Willecke et al., J. Biol. Chem. 246:5264-5272 (1971).
Lehninger, A. L., Short Course in Biochemistry, Work Publishers, Inc., New York, NY (1973).
Lam Lapyuen H.
McArthur Hamish A. I.
Wax Richard G.
Benson Gregg C.
Marx Irene
Pfizer Inc.
Richardson Peter C.
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