Cultured inner cell mass cell lines derived from bovine or porci

Details Cultured inner cell mass cell lines derived from bovine or porci Cultured inner cell mass cell lines derived from bovine or porci

1996-04-01

1999-05-18

Stanton, Brian R.

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Method of co-culturing cells

435325, 435378, 435379, 435380, 435381, 800 15, 800 17, 800 21, A01K67/027

Patent

active

059050420

ABSTRACT:
Novel cultured inner cell mass (CICM) cells, and cell lines, derived from ungulates, in particular, pigs and cows, and methods for their preparation are provided. The subject CICMs possess similar morphology and express cell markers identically or substantially similarly to ICMs of undifferentiated developing embryos for prolonged culturing periods. Heterologous DNAs may be introduced into the subject CICM cells and cell lines to produce transgenic cells useful for the production of transgenic embryos, fetuses and/or offspring, e.g., by nuclear transfer procedures.

REFERENCES:
patent: 5523226 (1996-06-01), Wheeler
Stice et al., "Pluripotent Bovine Embryonic Cell Lines Direct Embryonic Dlopment Following Nuclear Transfer", Biology of Reproduction, vol. 54, No. 1, Jan. 1996, pp. 100-110.
Cibelli J.B. et al., "Production of germline chimeric bovine fetuses from transgenic enbryonic stem cells", Theriogenology, vol. 47, No. 1, Jan. 1997, p. 241.
First et al, Systems for Production of Calves from Cultured Bovine Embryonic Cells, Reproduction, Fertility, and Development, vol. 6, pp. 553-562 (1994).
Bartlett et al, Evaluation of extracellular matrices and the plasminogen activator system in sheep inner cell mass and trophectodermal outgrowth in vitro, Biology of Reproduction, vol. 52, pp. 1426-1445 (1995).
Talbot et al, In vitro pluripotency of epiblasts derived from bovine blastocysts, Molecular Reproduction and Development, vol. 42, pp. 35-52 (1995).
Talbot et al, Culturing the epiblast cells of the pig blastocyst. In Vitro Cellular and Development Biology, vol. 29A, pp. 543-554 (Jul. 1993).
Annelies et al, Isolation and Characterization of Permanent Cell Lines from Inner Cell Mass Cells of Bovine Blastocysts, Molecular Reproduction and Development, vol. 40, pp. 444-454 (1995).
Collas et al, Nuclear Transplantation by Microinjection of Inner Cell Mass and Granulosa Cell Nuclei, Molecular Reproduction and Development, vol. 38, pp. 264-267 (1994).
Sims et al, Production of calves by transfer of nuclei from cultured inner cell mass cells, Proceedings of the National Academy of Sciences, USA, vol. 90, pp. 6143-6147 (Jun. 1993).
Seamark, R. et al (1994). Reproduction, Fertility and Development 6, 653-7.
Bradley, A. et al (1992). Bio Technology 10, 534-539.
Kappel, C. et al (1992). Current Opinion in Biotechnology 3, 548-553.
Sims, M. et al (1994). Proc. Natl. Acad. Sci USA 91, 6143-7.
Callard, R. et al (1994). The Cytokine Facts Brdc, Academic Press, pp. 163-167.
Talbot, N. et al (1993). In Vitro Cellular and Developmental Biology 29A, 543-554.

Affiliated with

Also associated with

Rating

Cultured inner cell mass cell lines derived from bovine or porci does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cultured inner cell mass cell lines derived from bovine or porci, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cultured inner cell mass cell lines derived from bovine or porci will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1759366