Cultured cells from pancreatic islets

Details Cultured cells from pancreatic islets Cultured cells from pancreatic islets

2007-01-02

2007-01-02

Nguyen, Dave Trong (Department: 1632)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Primate cell, per se

C435S325000

Reexamination Certificate

active

10497508

ABSTRACT:
A cell composition of endocrine progenitor cells derived from mammalian pancreatic islet cells that can be trans-planted into a diabetic patient such that the cells of the cell composition differentiates into functioning insulin-producing beta cells.

REFERENCES:
Levin F, No pancreatic endocrine stem cells?, 2004, NEJM, vol. 351, pp. 1024-1026.
Beattie GM, Sustained proliferation of PDX-1 cells derived from human islets, 1999, Diabetes, vol. 48, pp. 1013-1019.
Esni F, Orgin of exocrine pancreatic cells from nestin-positive precursors in developing mouse pancreas, 2004, Mech. of Develop. vol. 121, pp. 15-25.
rothr KI, Challenges facing islet transplantation for the treatment of type 1 diabetes-mellitus, 2004, JCI, vol. 114, pp. 877-883.

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