Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing
Reexamination Certificate
2002-07-25
2008-12-30
Davis, Ruth A (Department: 1651)
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
C435S325000, C435S347000, C435S373000
Reexamination Certificate
active
07470424
ABSTRACT:
Parenchymal cells are cultivated on cultivated endothelial cells or cultivated fibroblasts which have been separated by a surface of a specific hydrophilic polymer, and which have been patterned. A culture which contains thus formed patterned spheroids of cultivated parenchymal cells is thereby provided by this invention. This culture maintains a function which is specific to the parenchymal cells over a long period of time.
REFERENCES:
patent: 5976826 (1999-11-01), Singhvi et al.
patent: 6132979 (2000-10-01), Murakami
van Kooten et al., “Influence of substratum wettability on the strength of adhesion of human fibroblasts”, Biomaterials, 1992, 13(13):897-904.
Takezawa et al., Journal of Cell Science, 101, 495-501, 1992.
Horiike Yasuhiro
Kataoka Kazunori
Nagasaki Yukio
Okano Teruo
Otsuka Hidenori
Davis Ruth A
Transparent Inc.
Wenderoth , Lind & Ponack, L.L.P.
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