Culture of human embryonic stem cells on a matrix with TGFB1...

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Method of regulating cell metabolism or physiology

Reexamination Certificate

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C435S380000, C435S402000

Reexamination Certificate

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07955851

ABSTRACT:
The present invention is of methods of establishing and propagating human embryonic stem cell lines using feeder cells-free, xeno-free culture systems and stem cells which are capable of being maintained in an undifferentiated, pluripotent and proliferative state in culture which is free of xeno contaminants and feeder cells.

REFERENCES:
patent: 7592175 (2009-09-01), Amit et al.
patent: 2005/0038146 (2005-02-01), Fish et al.
patent: 2006/0051862 (2006-03-01), Amit et al.
patent: 2001-017163 (2001-01-01), None
patent: WO 99/20741 (1999-04-01), None
patent: WO 01/51616 (2001-07-01), None
patent: WO 01/88104 (2001-11-01), None
patent: WO 03/029443 (2003-04-01), None
patent: WO 2004/055155 (2004-07-01), None
Verfailffie, C.M. Adult Stem Cells: Assessing the Case for Pluripotency. Trends in Cell Biology, 2002, vol. 12, pp. 502-508.
Li et al. Leukemia Inhibitory Factor-Expressing Human Embryonic Fibroblasts as Feeder Cells for Human Embryonic Germ Cells. Cells Tissues Organs, 2007, vol. 186, pp. 221-228.
Communication Pursuant to Rules 109 and 110 EPC Dated Jul. 27, 2005 From the European Patent Office Re.: Application No. 03813286.6.
Office Action Dated Dec. 14, 2008 From the Israeli Patent Office Re.: Application No. 168984.
Office Action Dated Mar. 30, 2007 From the Patent Office of the People's Republic of China Re.: Application No. 200380109688.7.
Official Action Dated Sep. 15, 2008 From the US Patent and Trademark Office Re.: U.S. Appl. No. 10/537,784.
Examiner's Report Dated May 12, 2008 From the Australian Government, IP Australia Re.: Application No. 2003303071.
International Preliminary Examination Report Dated Jan. 25, 2006 From the International Preliminary Examining Authority Re.: Application No. PCT/IL03/01030.
Notice of Allowance Dated May 15, 2009 From the US Patent and Trademark Office Re.: U.S. Appl. No. 10/537,784.
Office Action Dated Jan. 9, 2009 From the State Intellectual Property Office of the People's Republic of China Re.: Application No. 200380109688.7.
Office Action Dated Dec. 14, 2008 From the Israeli Patent Office Re.: Application No. 168984 and Its Translation Into English.
Official Action Dated Oct. 9, 2007 From the US Patent and Trademark Office Re.: U.S. Appl. No. 10/537,784.
Official Action Dated Jan. 28, 2008 From the US Patent and Trademark Office Re.: U.S. Appl. No. 10/537,784.
Supplementary European Search Report Dated Jan. 26, 2007 From the European Patent Office Re.: Application No. 03813286.6.
Translation of Notice of Reason for Rejection Dated Oct. 2, 2009 From the Japanese Patent Office Re.: Application No. 2004-560155.
Written Opinion Dated Nov. 25, 2005 From the International Preliminary Examining Authority Re.: Application No. PCT/IL03/01030.
Amit et al. “Clonially Derived Human Embryonic Stem Cell Lines Maintain Pluripotency and Proliferative Potential for Prolonged Periods of Culture”, Developmental Biology, 227: 271-278, 2000.
Amit et al. “Feeder-Layer- and Serum-Free Culture of Human Embryonic Stem Cells”, Biology of Reproduction, 70: 837-845, 2004.
Amit et al. “Human Feeder Layers for Human Embryonic Stem Cells”, Biology of Reproduction, 68: 2150-2156, 2003.
Goldsborough et al. “Serum-Free Culture of Murine Embryonic Stem (ES) Cells”, Focus, 20(1): 9-12, 1998.
Murdoch et al. “Human Embryonic Derived Hematopoietic Repopulating Cells Require Distinct Factors to Sustain In Vivo Repoplating Function”, Experimental Hematology, 30: 598-605, 2002.
Pei et al. “Serum Free Culture of Rhesus Monkey Embryonic Stem Cells”, Archives of Andrology, 49: 331-342, 2003.
Schuldiner et al. “Effects of Eight Growth Factors on the Differentiation of Cells Derived From Human Embryonic Stem Cells”, Proc. Natl. Acad. Sci. USA, 97(21): 11307-11312, 2000.
Sigma “Tissue Culture Media and Reagents. Attachment and Matrix Factors”, Biochemical Organic Compounds. Diagnostic Reagents, The Sigma Catalog, p. 1389, 1992.
Thomson et al. “Embryonic Stem Cell Lines Derived From Human Balstocysts”, Science, 282: 1145-1147, 1998.
Xu et al. “Feeder-Free Growth of Undifferentiated IIuman Embryonic Stem Cells”, Nature Biotechnology, 19(10): 971-974, 2001.
Communication Pursuant to Article 94(3) EPC Dated Nov. 27, 2009 From the European Patent Office Re.: Application No. 03813286.6.
Response Dated Dec. 20, 2009 to Notice of Reason for Rejection of Oct. 2, 2009 From the Japanese Patent Office Re.: Application No. 2004-560155.
Response Dated Dec. 30, 2009 to Office Action of Aug. 30, 2009 From the Israel Patent Office Re.: Application No. 168984.
Richards et al. “Human Feeders Support Prolonged Undifferentiated Growth of Human Inner Cell Masses and Embryonic Stem Cells”, Nature Biotechnology, Technical Report, XP002335247, 20: 933-936, Sep. 2002.
Requisition by the Examiner Dated Feb. 25, 2010 From the Canadian Intellectual Property Office Re.: Application No. 2,508,880.
Response Dated Jun. 7, 2010 to Decision of Rejection of Apr. 2, 2010 From the Japanese Patent Office Re.: Application No. 2004-560155.
Response Dated May 25, 2010 to Communication Pursuant to Article 94(3) EPC of Nov. 27, 2009 From the European Patent Office Re.: Application No. 03813286.6.
Translation of Official Decision of Rejection Dated Apr. 2, 2010 From the Japanese Patent Office Re.: Application No. 2004-560155.
Robertson “NIH Sacrifies Commercial Rights in WiCell Deal”, Nature Biotechnology, 19: 1001, Nov. 2001.
Zhang “Feeder Layer- and Serum-Free Culture of Rhesus Monkey Embryonic Stem Cells”, Reproductive BioMedicine Online, 13(3): 412-420, 2006.
Response Dated Aug. 23, 2010 to Requisition by the Examiner of Feb. 25, 2010 From the Canadian Intellectual Property Office Re.: Application No. 2,508,880.

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