Culture media for inactivation of bacterial growth inhibitors

Details Culture media for inactivation of bacterial growth inhibitors Culture media for inactivation of bacterial growth inhibitors

1980-05-08

1982-07-20

Bernstein, Hiram

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

424230, C12N 120

Patent

active

043406793

ABSTRACT:
This invention encompasses methods and reagents for inactivation of bacterial growth inhibitors present in blood, serum or plasma. It has been found that salicylates and closely related compounds will neutralize bacterial growth inhibitors present in the blood of many patients. The addition of salicylate to conventional growth medium also provides a reagent for monitoring the antibiotic levels in blood by enabling measurement of the effect of the antibiotic against a standard test organism without interference from the bacterial growth inhibitor present in sera.

REFERENCES:
patent: 3671399 (1972-06-01), Cekoric et al.
A Compilation of Culture Media-Levine et al., Williams & Wilkins Co., 1930, Baltimore.

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