Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form
Reexamination Certificate
2006-03-07
2006-03-07
Spear, James M. (Department: 1618)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Particulate form
C424S489000, C424S493000, C424S494000
Reexamination Certificate
active
07008646
ABSTRACT:
A dry powder cubic gel precursor comprising an encapsulating compound, an amphiphile capable of forming a cubic liquid crystalline phase, and optionally a solvent. The encapsulating compound (A), amphiphile (B), and optional solvent (C) are present in mass fractions relative to each other such that 1.0=a+b+c wherein a is the mass fraction of A, b is the mass fraction of B, and c is the mass fraction of C. Further, 1.0>a>0, 1.0>b>0, 1.0>c>0 and a, b, and c do not fall within a cubic liquid crystalline phase region on a phase diagram representing phase behavior of A, B, and C.
REFERENCES:
patent: 5531925 (1996-07-01), Landh et al.
patent: 5756108 (1998-05-01), Ribier et al.
patent: 5811406 (1998-09-01), Szoka, Jr. et al.
patent: 5972373 (1999-10-01), Yajima et al.
patent: 6017388 (2000-01-01), Yuan
patent: 6299798 (2001-10-01), Guerin et al.
patent: 6656385 (2003-12-01), Lynch et al.
patent: 2002/0153509 (2002-10-01), Lynch et al.
patent: WO 96/03056 (1996-02-01), None
patent: WO 99/12640 (1999-03-01), None
patent: WO 99/47004 (1999-09-01), None
patent: WO 00/23517 (2000-04-01), None
patent: WO 01/68139 (2001-09-01), None
Gustafsson, J. et al., “Submicron Particles of Reversed Lipid Phases in Water Stabilized by a Nonionic Amphiphilic Polymer”, LANGMUIR, 13, pp. 6964-6971 (1997).
Hyde, S. et al., “Cubic Phases”, The Language Of Shape, Chapter 5, pp. 203-208 (1997).
Laughlin, R. G., “An Expedient Technique for Determining Solubility Phase Boundaries in Surfactant-Water Systems”, Journal Of Colloid And Interface Science, vol. 55, No. 1, pp. 239-242 (1976).
Hecht, E., “Birefringence”, OPTICS, 3rdEdition, pp. 330-342 (1998).
Rosevear Ph.D., F. B., “Liquid Crystals: The Mesomorphic Phases of Surfactant Compositions”, Journal Of Society Of Cosmetic Chemists, 19, pp. 581-594 (1968).
Laughlin, R. G., Surfactant and Nonsurfactant Behavior, The Aqueous Phase Behavior Of Surfactants, Chapter 9, p. 255 (1994).
Porter, M. R., “Nonionics”, Handbook Of Surfactants, 2ndEdition, pp. 188-236.
Lynch, M. L., et al., “Aqueous-Phase Behavior and Cubic Phase-Containing Emulsions in the C12E2-Water System”, LANGMUIR, 16, pp. 3537-3542 (2000).
Laughlin, R. G., “The Determination Of Phase Diagrams”, The Aqueous Phase Behavior Of Surfactants, Appendix 4, pp. 521-546 (1994).
J. S. Kim, et al.,Drug Formulations that Form a Dispersed Cubic Phase when Mixed with Water, Procced. Int'l. Symp. Control. Rel. Bioact. Mater., 27 (2000) Controlled Release Society, Inc., pp. 1118 & 1119.
Lynch Matthew Lawrence
Small, II William Broderick
Spicer Patrick Thomas
Frost Brown Todd LLC
Spear James M.
LandOfFree
Cubic liquid crystalline compositions and methods for their... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Cubic liquid crystalline compositions and methods for their..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cubic liquid crystalline compositions and methods for their... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3526057