CTIP2 expression in squamous cell carcinoma

Details CTIP2 expression in squamous cell carcinoma CTIP2 expression in squamous cell carcinoma

2009-07-17

2011-12-06

Rawlings, Stephen (Department: 1643)

Organic compounds -- part of the class 532-570 series

Organic compounds

Boron containing

C435S007100, C435S007230, C436S064000, C436S501000, C530S350000, C530S387700, C530S388800, C530S389700, C536S023500

Reexamination Certificate

active

08071815

ABSTRACT:
The present disclosure provides methods of diagnosing and staging squamous cell carcinomas, for instance head and neck (HNSCC), by detecting chicken ovalbumin upstream promoter-transcription factor-interacting protein 2 (CTIP2) expression. For example, it is demonstrated herein that expression of CTIP2 is increased in SCC relative to a corresponding normal sample. Also included are kits for detecting SCC, as well as methods for identifying CTIP2 inhibitors.

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