Crystals of serum albumin for use in genetic engineering and rat

Details Crystals of serum albumin for use in genetic engineering and rat Crystals of serum albumin for use in genetic engineering and rat

1994-12-06

1996-12-17

Elliott, George C.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Albumin

530362, 530364, 530418, 530419, 530421, 530829, 530830, C07K 14765, C07K 1476, C07K 1447, C07K 130

Patent

active

055854664

ABSTRACT:
Serum albumin crystal forms have been produced which exhibit superior x-ray diffraction quality. The crystals are produced from both recombinant and wild-type human serum albumin, canine, and baboon serum albumin and allow the performance of drug-binding studies as well as genetic engineering studies. The crystals are grown from solutions of polyethylene glycol or ammonium sulphate within prescribed limits during growth times from one to several weeks and include the following space groups: P2.sub.1, C2, P1.

REFERENCES:
patent: 4833233 (1989-05-01), Carter
patent: 4886646 (1989-12-01), Carter et al.
Ho et al. "X-Ray & Primary Structure of Horse Serum Albumin (Eguus caballus) at O.27nm Resolution" Fur. J. Biochem. 215 205-212 1993.

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