Crystals of quinolinecarboxylic acid derivative solvate

Details Crystals of quinolinecarboxylic acid derivative solvate Crystals of quinolinecarboxylic acid derivative solvate

2004-04-28

2009-11-03

Bernhardt, Emily (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

C514S253030

Reexamination Certificate

active

07612205

ABSTRACT:
A main object is to provide a crystal of 6-fluoro-1-methyl-7-[4-(5-methyl-2-oxo-1,3-dioxolen-4-yl)-methyl-1-piperazinyl]-4-oxo-4H-[1,3]thiazeto[3,2-a]quinoline-3-carboxylic acid acetonitrile solvate (Compound B) which is an intermediate for producing preferentially the type III crystal of 6-fluoro-1-methyl-7-[4-(5-methyl-2-oxo-1,3-dioxolen-4-yl)methyl-1-piperazinyl]-4-oxo-4H-[1,3]-thiazeto[3,2-a]quinoline-3-carboxylic acid (Compound A). A crystal of Compound B can be preferentially precipitated by controlling the supersaturation concentration in crystalization using acetonitrile as a solvent. Subsequently, the type III crystal of Compound A can be produced by performing desolvation of the crystal.

REFERENCES:
patent: 5086049 (1992-02-01), Kise et al.
patent: 1-294680 (1989-11-01), None
English Translation for Kakemi et al. Iyakuhin Kenkyo, vol. 28,No. 1, pp. 1-11 (1997).
Kakemi, Kazuo et al.; “Chemical Structure, Physico-chemical Properties and Stability of Prulifloxacin”; Iyakuhin Kenkyu vol. 28, No. 1, Jan. 20, 1997, pp. 1-11; p. 4., 2.1 Kessho Takei no ko.

Affiliated with

Also associated with

Rating

Crystals of quinolinecarboxylic acid derivative solvate does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Crystals of quinolinecarboxylic acid derivative solvate, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Crystals of quinolinecarboxylic acid derivative solvate will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4093881