Crystals

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C546S275400

Reexamination Certificate

active

10525709

ABSTRACT:
Obtaining the crystal of 4,6-dimethyl-4′-[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]nicotinanilide having excellent activity of inhibiting Ca2+release-activated Ca2+channel and suppressing IL-2 production to find that the compound includes the presence of two types of polymorphic crystals and that any of the crystals is preferable as a raw material for producing pharmaceutical compositions.

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patent: 6958339 (2005-10-01), Kubota et al.
patent: 2001/0011090 (2001-08-01), Kubota et al.
patent: 1024138 (2000-08-01), None
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patent: WO99/19303 (1999-04-01), None
patent: WO99/51580 (1999-10-01), None
patent: WO99/62885 (1999-12-01), None
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