Crystallization of AKT3

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving transferase

Reexamination Certificate

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C435S194000, C702S027000

Reexamination Certificate

active

10601311

ABSTRACT:
Provided are crystals relating to AKT3 and its various uses.

REFERENCES:
patent: 6881555 (2005-04-01), Guo et al.
patent: 2004/0137518 (2004-07-01), Lambert et al.
Wiencek et al. New strategies for protein crystal growth. Ann. Rev. Biomed. Eng. 1999, 1, 505-534.
Gilliland et al. Crystallization of biological molecules for X-ray diffraction studies. Current Opinion in Structure Biology 1996, 6, 595-603.
Ke et al. Crystallization of RNA and RNA-protein complexes. Methods 34, 2004, 408-414.
Brunger, Axel T. et al., “Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination”, Acta Cryst. (1998) D54, pp. 905-921.
Hegyi, Heidi et al., “The Relationship between Protein Structure and Function: a Comprehensive Survey with Application to the Yeast Genome”, J. Mol. Biol. (1999) 288, 147-164.
Yang, Jing, et al., “Molecular Mechanism for the Regulation of Protein Kinase B/Akt by Hydrophobic Motif Phosphorylation”, Molecular Cell, vol. 9, (2002), pp. 1227-1240.

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