Crystallization of a protein with a sulphur salt

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for...

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435189, 435195, 435198, 435202, 435219, 435220, 435221, 435816, 210702, C12N 900, C12N 914, B01O 2100

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active

060664819

ABSTRACT:
The present invention relates to a method for crystallization of a protein obtained from a protein-containing solution which involves (a) treating the protein-containing solution with a salt containing a sulphur atom having an oxidation state less than 6, and (b) recovering the protein in crystalline form.

REFERENCES:
patent: 1826467 (1931-10-01), Harteneck
patent: 3700561 (1972-10-01), Ziffer
patent: 3795586 (1974-03-01), Ziller et al.
patent: 5510461 (1996-04-01), Meuer et al.
Lang et al. Enzyme Micorb. 14(6). pp. 479-485, 1992.
McPherson, Eur. J. Biochem, vol. 189, pp. 1-23 (1990).
Judge et al., Biotechnology and Bioengineering, vol. 48, pp. 316-323 (1995) .

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