Crystalline xamoneline tartrate

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514340, 546276, 546277, A61K 31445, C07D41704

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active

058344950

ABSTRACT:
The invention provides crystalline 3-(4-hexyloxy-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methylpyridine (+) L-hydrogentartrate, its preparation and use as a therapeutic agent.

REFERENCES:
patent: 5041455 (1991-08-01), Sauerberg
patent: 5043345 (1991-08-01), Sauerberg
patent: 5260311 (1993-11-01), Sauerberg
patent: 5264444 (1993-11-01), Sauerberg
Sauerberg et al., J. Med. Chem., vol. 35, pp. 2274-2283 (1992).
Berger et al "Pharmaceutical Salts" J. Pharm. Sci. 66(1) 1-19 (1977).
Hamilton et al., Journal of Chromatography, 613 (1993) pp. 365-270.
Levine et al., Life Science, vol. 52, Nos. 5/6 (1993).

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