Crystalline tiotropium bromide monohydrate, processes for...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S291000, C514S304000, C546S086000, C546S089000, C546S091000

Reexamination Certificate

active

06908928

ABSTRACT:
Crystalline monohydrate of (1α,2β,4β,5α,7β)-7-[(hydroxydi-2-thienylacetyl)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane bromide (tiotropium bromide monohydrate), processes for the preparation thereof, pharmaceutical compositions thereof, and their use.

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Accession No. 2002:1138, tiotropium bromide salt, CAS Reg. No. 136310-93-5, derivative of 139404-48-1, tiotropium bromide hydrate, printout of DRUGPAT reference.
U.S. Patent Application No. 2003/0087927 -Crystalline Anticholinergic, Processes for Preparing it and its use for Preparing a Pharmaceutical Composition published May 8, 2003.
U.S. Patent Application, Crystlline Micronisate, Process for the Manufature thereof and use thereof for the Preparation of a Medicament, accorded Ser. No. 10/385,175, filed Mar. 5, 10, 2003, for Docket No. 1/1310, Bender, H. et al.
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