Crystalline potassium salt of lipoxin A 4 analogs

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof

Reexamination Certificate

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C562S472000

Reexamination Certificate

active

08049035

ABSTRACT:
This invention is directed to the crystalline potassium salt of a lipoxin A4analog of Formula (I):processes for preparing the crystalline potassium salts, methods for using them to treat disease-states characterized by inflammation, and pharmaceutical compositions comprising such crystalline potassium salts.

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Leonard, M.O. et al., “15-Epi-16-(Para-Fluorophenoxy)-Lipoxin A4-Methyl Ester, a Synthetic Analougue of 15-epi-Lipoxin A4, Is Protective in Experimental Ischemic Acute Renal Failure,” J. Am. Soc. Nephrol, 2002, vol. 13, No. 6, pp. 1657-1662.

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