Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...
Reexamination Certificate
2005-04-02
2010-06-08
Wilson, James O (Department: 1624)
Organic compounds -- part of the class 532-570 series
Organic compounds
Nitrogen attached directly or indirectly to the purine ring...
Reexamination Certificate
active
07732601
ABSTRACT:
This invention relates to the methanesulfonic acid addition salts of Imatinib and to the synthesis thereof. In particular, this invention relates to the synthesis of crystalline α-form of Imatinib methanesulfonate. Furthermore, the invention is directed to a novel acid addition salt of 4-(4-methylpiperazin-1-ylmethyl)-N-[4-methyl-3-[(4-pyridin-3-yl)pyrimidin-2-ylamino)phenyl]benzamide with two molecules of methanesulfonic acid and to the polymorphic forms thereof, as well as to their pharmaceutical compositions.
REFERENCES:
patent: 99/03854 (1999-01-01), None
patent: 2004/026930 (2004-04-01), None
Cmoch Piotr
Fraczek Urszula
Glice Magdalena
Kaczmarek Lukasz
Korczak Katarzyna
Instytut Farmaceutyczny
Jaisle Cecilia M
Matthias Scholl, PC
Scholl Matthias
Wilson James O
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