Crystalline pivaloyloxymethyl d(-)-.alpha.-aminobenzylpenicillin

Details Crystalline pivaloyloxymethyl d(-)-.alpha.-aminobenzylpenicillin Crystalline pivaloyloxymethyl d(-)-.alpha.-aminobenzylpenicillin

1973-09-21

1976-05-11

Rizzo, Nicholas S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424271, C07D50120

Patent

active

039562794

ABSTRACT:
The present invention relates to pivaloyloxymethyl D(-)-.alpha.-aminobenzylpenicillinate of the formula I in a novel and improved form, i.e. the crystalline form ##SPC1##
To methods of producing said crystalline pivaloyloxymethyl D(-)-.alpha.-aminobenzylpenicillinate and to pharmaceutical preparations containing said crystalline pivaloyloxymethyl D(-)-.alpha.-aminobenzylpenicillinate.
Crystalline pivaloyloxymethyl D(-)-.alpha.-aminobenzylpenicillinate has no bitter taste, is only slightly soluble in water, and is stable and readily absorbable.

REFERENCES:
patent: 3674776 (1972-07-01), Long et al.
patent: 3697507 (1972-10-01), Freperiksen et al.

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