Crystalline N-(S-3-methylheptanoyl)-D-gamma-glutamyl-glycyl-D-al

Details Crystalline N-(S-3-methylheptanoyl)-D-gamma-glutamyl-glycyl-D-al Crystalline N-(S-3-methylheptanoyl)-D-gamma-glutamyl-glycyl-D-al

1993-05-27

1994-12-06

Dees, Jose G.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Tripeptides, e.g., tripeptide thyroliberin , etc.

530333, 530338, C07K 110, C07K 508

Patent

active

053711874

ABSTRACT:
A process and intermediates for the manufacture of S-3-methylheptanoic acid from S-citronellol; a novel crystalline form of immunoregulatory N-(S-3-methlylheptanoyl)-D-gamma-glutamyl-glycyl-D-alanine, an immunoregulatory agent; and an improved process and intermediates therefor.

REFERENCES:
patent: 3985722 (1976-10-01), Yoshida et al.
patent: 4401658 (1983-08-01), Bouchaudon et al.
patent: 4564620 (1986-01-01), Ohno et al.
patent: 4565653 (1986-01-01), Ives et al.
patent: 4767743 (1988-08-01), Rizzi
Appolzer et al., Helvetica Chimica Acta, vol. 68, pp. 212-215 (1985).
Posner et al., J. Am. Chem. Soc., vol. 103, No. 10, pp. 2886-2888 (1981).
Mukayama et al., Chemistry Letters, pp. 913-916 (1981).
Soai et al., J. Chem. Soc., Chem. Commun., pp. 469-470 (1985).
Meyers et al., J. Am. Chem. Soc., vol. 98, No. 8, pp. 2290-2294 (1976).
Chemical Abstracts, vol. 47, Abstract No. 9268d (1953); abstracting Gol'mov, Zhur. Obshchei Khim., vol. 22, 1944-53 (1952).
Eschinagi, J. Org. Chem., vol. 26, 3072-3076 (1961).
House, "Modern Synthetic Reactions", 2nd ed., Benjamin, Inc., pp. 263, 269, 274-275 (1972).
Lebel et al., J. Org. Chem., vol. 36, pp. 2440-2448 (1971).
Poulson et al., Organic Chemistry, pp. 1025-1031 (1980).
Herberman et al., 13th International Congress of Chemotherapy, pp. 203/19-203/35 (1983).

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