Crystalline lysocellin compositions and method of making

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D30910

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048929603

ABSTRACT:
Crystalline lysocellin compositions, and method of making them. These compounds are useful for promoting growth and feed efficiency in food producing mammals by administering growth promoting amounts of the compounds to such mammals. In particular, the crystalline free acid and the crystalline zinc, copper and manganese of lysocellin can be made according to the disclosed methods.

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Westley, J. W.: Polyether Antibiotics: Versatile Carboxylic Acid Ionophores Produced by Streptomyces, Advances in Applied Microbiology 22:177-223, 1977.
Ebata, E., et al: Lysocellin, A New Polyether Antibiotic, Journal of Antibiotics 28(2):118-121, 1975.
Otake, N., et al: The Assignment of the .sup.13 C--NMR Spectrum of Lysocillin and Its Biosynthesis, Agric. Biol. Chem. 42(10):1879-1886, 1978.
N. Otake et al., J.C.S. Chem. Comm., 1975, pp. 92-93.
J. W. Westley, Advances in Applied Microbiology, 22:177-223 (1977).
Martin et al., Chem. Abstract, 94, 137 806c (1981) (Abstract of Ger. Offen. 3,026,408).
Martin et al., Chem. Abstract, 95, 103,314w (1981) (Abstract of Brit. Pat. 2,055,094).

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