Crystalline hydrate of oral cephalosporin and its composition

Details Crystalline hydrate of oral cephalosporin and its composition Crystalline hydrate of oral cephalosporin and its composition

1987-07-01

1989-03-14

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

424452, 424456, 514202, A61K 31545, C07D50120

Patent

active

048125610

ABSTRACT:
An antibacterial, 7.beta.-[(Z)-2-(2-aminothiazol-4-yl)-4-carboxybut-2-enoylamino]-3-cephem-4 -carboxylic acid is stable in a (di or tri)-hydrate crystal form. A pharmacologically effective amount of this hydrate is filled in a gelatin hard capsule sealed by a band of gelatin to make a stable composition for clinical use after storage for a long time.

REFERENCES:
patent: 4390694 (1983-06-01), Ohnishi
patent: 4634697 (1987-01-01), Hamashima
patent: 4731361 (1988-03-01), Hamashima
patent: 4748170 (1988-05-01), Hamashima

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