Crystalline forms of gatifloxacin

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C546S156000

Reexamination Certificate

active

07396839

ABSTRACT:
Provided are novel crystalline forms of gatifloxacin, denominated forms L, M, P, Q, S, and T1, and methods for making them. Also provided are methods of transforming the novel crystalline forms of gatifloxacin of the present invention to other crystalline forms of gatifloxacin.

REFERENCES:
patent: 5880283 (1999-03-01), Matsumoto et al.
patent: 6413969 (2002-07-01), Raghavan et al.
patent: 0 629 621 (1994-12-01), None
patent: 0 805 156 (1997-11-01), None
patent: WO 02 22126 (2002-03-01), None
patent: WO 2003/086402 (2004-10-01), None
John Haleblian et al., “Pharmaceutical Applications of Polymorphism,” Journal of Pharmaceutical Sciences, vol. 58, No. 8, Aug. 1969, pp. 911-929.
John K. Haleblian, “Characterization of Habits and Crystalline Modification of Solids and Their Pharmaceutical Applications,” Journal of Pharmaceutical Sciences, vol. 64, No. 8, Aug. 1975, pp. 1269-1288.
G. Michael Wall, “Pharmaceutical Applications of Drug Crystal Studies,” Pharmaceutical Manufacturing, vol. 3, No. 2, Feb. 1986, pp. 33-42.

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