Crystalline forms of endo-2,3-dihydro-N-(8-methyl)-8-azabicyclo[

Details Crystalline forms of endo-2,3-dihydro-N-(8-methyl)-8-azabicyclo[ Crystalline forms of endo-2,3-dihydro-N-(8-methyl)-8-azabicyclo[

1994-06-22

1995-11-21

Richter, Johann

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548126, A61K 3146, C07D45112

Patent

active

054687586

ABSTRACT:
Crystalline and pharmacologically active monohydrates of endo-2,3-dihydro-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2-oxo-1H-benzimi dazole-1-carboxamide hydrochloride and of endo-3-ethyl-2,3-dihydro-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2-oxo-1H -benzimidazole-1-carboxamide hydrochloride.

REFERENCES:
patent: 5223511 (1993-06-01), Turconi et al.
Sagrada, A; Turconi, M.; Bonali, P.; Schiantarelli, P., Micheletti, R.; Montagna, E; Nicolam M.; Algate, D. R.; Rimoldi, E. M.; and Donetti, A. Cancer Chemother. Pharmacol. (1991) 28:470-474.

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