Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2004-08-26
2008-11-04
Wilson, James O. (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C544S336000
Reexamination Certificate
active
07446107
ABSTRACT:
The invention provides novel soluble conazole crystalline forms (e.g. itraconazole, posaconazole and saperconazole) that include salts, co-crystals and related solvates useful as pharmaceuticals. The invention also provides pharmaceutical compositions comprising, and processes for making, these conazole crystalline forms. Methods of using such compositions for the treatment or prevention of systemic and local fungal, yeast, and dermatophyte infections are also provided.
REFERENCES:
patent: 3598123 (1971-08-01), Zaffaroni
patent: 3845770 (1974-11-01), Theeuwes et al.
patent: 3916899 (1975-11-01), Theeuwes et al.
patent: 4008719 (1977-02-01), Theeuwes et al.
patent: 4267179 (1981-05-01), Heeres et al.
patent: 4764604 (1988-08-01), Muller
patent: 4916134 (1990-04-01), Heeres et al.
patent: 5006513 (1991-04-01), Hector et al.
patent: 5059595 (1991-10-01), Le Grazie
patent: 5073543 (1991-12-01), Marshall et al.
patent: 5120548 (1992-06-01), McClelland et al.
patent: 5354556 (1994-10-01), Sparks et al.
patent: 5414997 (1995-05-01), Tailer
patent: 5474997 (1995-12-01), Gray et al.
patent: 5591767 (1997-01-01), Mohr et al.
patent: 5633015 (1997-05-01), Gilis et al.
patent: 5639476 (1997-06-01), Oshlack et al.
patent: 5661151 (1997-08-01), Saksena et al.
patent: 5674533 (1997-10-01), Santus et al.
patent: 5707975 (1998-01-01), Francois et al.
patent: 5733566 (1998-03-01), Lewis
patent: 5998413 (1999-12-01), Heeres et al.
patent: 2003/0096014 (2003-05-01), Sherman
patent: 2003/0224006 (2003-12-01), Zaworotko et al.
patent: 2004/0019211 (2004-01-01), Remenar et al.
patent: 2004/0176335 (2004-09-01), Childs
patent: 0310122 (1989-04-01), None
patent: 0283992 (1992-09-01), None
patent: WO 94/16733 (1994-08-01), None
patent: WO 95/17407 (1995-06-01), None
patent: WO 98/57967 (1998-12-01), None
patent: WO 01/41536 (2001-06-01), None
patent: WO 01/51919 (2001-07-01), None
patent: WO 01/97853 (2001-12-01), None
patent: WO 02/056878 (2002-07-01), None
patent: WO 02/062318 (2002-08-01), None
patent: WO 03/074474 (2003-09-01), None
patent: WO 03/101392 (2003-12-01), None
McCrone, Walter C., “Polymorphism”, in “The Physics and Chemistry of the Organic Solid State, vol. II”, Fox, David et al eds, Interscience, New York, pp. 725-767 (1965).
Vippagunta et al., “Crystalline solids”, Advanced Drug Delivery Reviews, 48, pp. 3-26 (2001).
Cacciapuoti et al., Antimicrob. Ag. Chemother., 44: p. 2017 (2000).
Callaghan et al., Conazole Dev. Ind. Pharm., vol. 8, pp. 335-369 (1982).
Dannaoui et al., J. Antimicrob. Chemother., 47: pp. 333-340 (2001).
Denning et al., Eur. J. Clin. Microbiol. Infect. Dis., 9: p. 693 (1990).
Dressman et al., Pharm. Res., 15(1): pp. 11-22 (1998).
Ebert, Pharm. Tech., 1(5): pp. 44-50 (1977).
Gascon et al., Eur. J. Clin. Pharmacol., 41: pp. 573-578 (1991).
Heeres et al., J. Med. Chem, 27: pp. 894-900 (1984).
Honig et al., J. Clin. Pharmacol., 33: pp. 1201-1206 (1993).
Imai et al., Intern. Med., 38(10): pp. 829-832 (1999).
Kim et al., J. Chromatog., 738: p. 93 (2000).
Kovacs et al., “New Type of Bridged Monoamino-β-Cyclodextrins”, J. of Inclusion Phenomena and Molecular Recognition in Chemistry, 25: pp. 53-56 (1996).
Lavrijsen et al., Lancet, 340: pp. 251-252 (1992).
Neuvonen et al., Clin. Pharmacol. Therap., 60: pp. 54-61 (1996).
Nomeir et al., Antimicrob. Ag. Chemother., 44: p. 727 (2000).
Odds, F.C., J. Antimicrob. Chemother., 24: p. 533 (1989).
Remenar et al., “Crystal Engineering of Novel Cocrystals of a Triazole Drug with 1,4-Dicarboxylic Acids”, J. Am. Chem. Soc., 125: pp. 8456-8457 (2003).
Saksena et al., Anti-Infectives: Recent Advances in Chemistry and Structure Activity Relationships (Royal Soc. Chem., Cambridge), pp. 180-199 (1997).
Tetrahedron Letters, 37: p. 5657 (1996).
Tetrahedron Letters, 43(18): pp. 3359-3363 (2002).
Van Cutsem et al., Antimicrob. Ag. Chemother., 33: p. 2063 (1989).
Villa et al., Rev. Inst. Med. Trop., Sao Paulo, pp. 231-234 (Jul.-Aug. 2000).
West, A., Solid State Chemistry and its Applications, Wiley, NY, pp. 358-365 (1988).
Aronhime, J., “Crystalline forms of pharmaceuticals and characterization thereof”, Oral Presentation, USPTO, Alexandria, VA, Mar. 8, 2005.
Desiraju, G., “Chemistry beyond the molecule”, Nature, 412: pp. 397-400 (2001).
Gavezzotti, A., “Are Crystal Structures Predictable?”, Acc. Chem. Res., 27: pp. 309-314 (1994).
Physician's Desk Reference, 56th ed., pp. 1800-1804 (2002).
Almarsson Orn
MacPhee Michael
Morissette Sherry
Peterson Matthew
Remenar Julius
Sackey Ebenezer
Transform Pharmaceuticals Inc.
Wilson James O.
LandOfFree
Crystalline forms of conazoles and methods of making and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Crystalline forms of conazoles and methods of making and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Crystalline forms of conazoles and methods of making and... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4023801