Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2004-11-17
2010-06-01
Wilson, James O (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C544S258000
Reexamination Certificate
active
07727987
ABSTRACT:
Crystal forms of (6R)-L-erythro-tetrahydrobiopterin dihydrochloride, hydrates and solvates and processes for their preparation are provided. These crystal forms are either intermediates for the preparation of stable polymorphic form B or are suitable for solid formulations.
REFERENCES:
patent: 4595752 (1986-06-01), Azuma et al.
patent: 4758571 (1988-07-01), Curtius et al.
patent: 6544994 (2003-04-01), Rabelink et al.
patent: 0 191 335 (1986-08-01), None
patent: WO 2005/065018 (2005-07-01), None
Arnold ,Phenylketonuria, eMedicine from webMD, Jun. 5, 2006, http://www.emedicine.com/PED/topic1787.htm.
Schircks Laboratories, Tetrahydrobiopterin, Sales restrictions, Jun. 2006, http://www.schircks.com/tablets/tablet—info.htm.
Disorders Index of the National Institute of Neurological Disorders and Stroke, Oct. 2006 http://www.ninds.nih.gov/disorders/disorder—index.htm?css=print.
Choi, et al., Tetrahydrobiopterin is Released from and Causes Preferential Death of Catecholaminergic Cells by Oxidative Stress, Molecular Pharmacology, vol. 58, No. 3, 2000, 633-640.
Galley, et al., Brit. J. Anaesthesia, 86(4): 578-80 (2001).
Tsai, et al., Psychosomatic Medicine 61:651-665 (1999).
Smith, MedPage Today, Apr. 20, 2007.
Khripak, et al., Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 844-846, Jun. 1975.
Schisla, et al., Zeolites, vol. 16, No. 2, Feb. 1996, pp. 221.
U.S. Appl. No. 60/520,767, Daniel Oppenheimer, filed Nov. 17, 2003.
U.S. Appl. No. 10/991,573, Daniel Oppenheimer, filed Nov. 17, 2004.
U.S. Appl. No. 11/143,887, Daniel Oppenheimer, filed Jun. 1, 2005.
U.S. Patent Publication No. 20060035900A1, published Feb. 16, 2006.
U.S. Appl. No. 11/542,310, Daniel Oppenheimer, filed Oct. 2, 2006.
Statement For The Record filed Feb. 25, 2008.
J. Biochem. 98, 1341-1348 (1985)—vol. 98, No. 5, 1985—Stereochemistry of Biopterin Cofactor and Facile Methods for the Determination of the Stereochemistry of a Biologically Active 5,6,7,8-Tetrahydropterin1,2,3, Sadao Matsuura et al.
Heterocycles, vol. 23, No. 12, 1985—pp. 3115-3120—Hydrogenation of Biopterin and Its Analogues; Application For The Convenient Procedure of Biopterin Cofactor and Related 5,8,7,8-Tetrahydropterins—Sadao Matsuura et al.
Chemistry Letters, pp. 735-738, 1984—The Chemical Society of Japan 1984—pp. 735-738—Highly Stereoselective Procedure for (6R)-Tetrahydrobiopterin Cofactor—Sadao Matsuura et al.
Schircks Laboratories—Tetrahydrobiopterin Tablets, Jan. 8, 2008.
Blatter Fritz
Egger Thomas
Groehn Viola
Moser Rudolf
Jaisle Cecilia M
Merck Eprova AG
Millen White Zelano & Branigan P.C.
Wilson James O
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