CRYSTALLINE FORMS OF 1S-[1ALPHA(2S*,3R*), 9ALPHA]6,...

Details CRYSTALLINE FORMS OF 1S-[1ALPHA(2S*,3R*), 9ALPHA]6,... CRYSTALLINE FORMS OF 1S-[1ALPHA(2S*,3R*), 9ALPHA]6,...

2005-09-20

2005-09-20

McKenzie, Thomas C. (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C540S460000

Reexamination Certificate

active

06946459

ABSTRACT:
Two new crystalline forms of 1S-[1alpha(2S*, 3R*), 9alpha]6, 10-dioxo-N-(2-ethoxy-5-oxo-tetrahydro-3-furany1)-9 [[(1-isoquinolyl) carbony1]amino]octahydro-6H-pyridazino [1,2-a][1,2]diazepin-1-carboxamide (anhydrous or hydrated), their preparation process and the pharmaceutical compositions containing them.

REFERENCES:
Randle, J.C. et al, Expert Opin. Investig. Drugs, 2001, vol. 10(7), pp. 1207-1209, Medline Abstract 11772244.
Giegel, D.A. et al, Ann. Reports Med. Chem., 33, 1998, 183-192.
Siegmund, B., Biochem. Pharmacol., vol. 64(1), 2002, pp. 1-8, Medline Abstract 12106600.

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