Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-05-19
2008-09-02
Wilson, James O (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C544S263000
Reexamination Certificate
active
07419982
ABSTRACT:
The present invention relates to crystalline forms of 5-chloro-6-{2,6-difluoro-4-[3-(methylamino)propoxy]phenyl}-N-[(1S)-2,2,2-trifluoro-1-methylethyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine salts; processes for the production thereof; pharmaceutical compositions thereof; and methods for inhibiting tumor growth therewith.
REFERENCES:
patent: 5593996 (1997-01-01), Pees et al.
patent: 5612345 (1997-03-01), Becher et al.
patent: 5750766 (1998-05-01), Krummel et al.
patent: 5756509 (1998-05-01), Pees et al.
patent: 5808066 (1998-09-01), Krummel et al.
patent: 5817663 (1998-10-01), Pees et al.
patent: 5854252 (1998-12-01), Pees et al.
patent: 5948783 (1999-09-01), Pees et al.
patent: 5955252 (1999-09-01), Goto et al.
patent: 5965561 (1999-10-01), Pees et al.
patent: 5981534 (1999-11-01), Pfrengle et al.
patent: 5985883 (1999-11-01), Pees et al.
patent: 5986135 (1999-11-01), Pfrengle et al.
patent: 5994360 (1999-11-01), Pfrengle et al.
patent: 6020338 (2000-02-01), Pfrengle et al.
patent: 6117865 (2000-09-01), Pees et al.
patent: 6117876 (2000-09-01), Pees et al.
patent: 6124301 (2000-09-01), Aven et al.
patent: 6204269 (2001-03-01), Pfrengle et al.
patent: 6242451 (2001-06-01), Pees et al.
patent: 6255309 (2001-07-01), Pees et al.
patent: 6268371 (2001-07-01), Sieverding et al.
patent: 6277856 (2001-08-01), Cotter et al.
patent: 6284762 (2001-09-01), Pfrengle et al.
patent: 6297251 (2001-10-01), Pees et al.
patent: 6387848 (2002-05-01), Aven et al.
patent: 6518275 (2003-02-01), Van Tuyl Cotter et al.
patent: 6521628 (2003-02-01), Cotter et al.
patent: 6699874 (2004-03-01), Cotter et al.
patent: 2002/0045631 (2002-04-01), Aven et al.
patent: 2002/0061882 (2002-05-01), Pees et al.
patent: 2002/0068744 (2002-06-01), Schmitt et al.
patent: 2002/0198222 (2002-12-01), Bruns et al.
patent: 2003/0055069 (2003-03-01), Pees et al.
patent: 2004/0097522 (2004-05-01), Gebauer et al.
patent: 2005/0030775 (2005-02-01), Lipcsei
patent: 2005/0090508 (2005-04-01), Zhang et al.
patent: 2005/0124635 (2005-06-01), Wu et al.
patent: 0 550 113 (1993-07-01), None
patent: 0 562 615 (1993-09-01), None
patent: 0 782 997 (1997-07-01), None
patent: 0 834 513 (1998-04-01), None
patent: 0 943 241 (1999-09-01), None
patent: 0 945 453 (1999-09-01), None
patent: 0 988 790 (2000-03-01), None
patent: 0 989 130 (2000-03-01), None
patent: 2 784 381 (2000-04-01), None
patent: WO-94/20501 (1994-09-01), None
patent: WO-98/41496 (1998-09-01), None
patent: WO-98/46607 (1998-10-01), None
patent: WO-99/41255 (1999-08-01), None
patent: WO-99/48893 (1999-09-01), None
patent: WO-00/18227 (2000-04-01), None
patent: WO-01/35738 (2001-05-01), None
patent: WO-02/02563 (2002-01-01), None
patent: WO-02/38565 (2002-05-01), None
patent: WO-02/46195 (2002-06-01), None
patent: WO-02/50077 (2002-06-01), None
patent: WO-02/067679 (2002-09-01), None
patent: WO-02/083676 (2002-10-01), None
patent: WO-03/008416 (2003-01-01), None
Berge et. al., J. Pharm. Sci. 1997, 66(1), p. 1-19.
Brittain et. al., 1999, “Effects of Pharmaceutical Processing on drug polymoprhys and solvates.”In Polymorphism in Pharmaceutical Solids, pp. 331-361.
http://www.expresspharmaonline.com/20031012/edit02.shtml (3 pages) Jul. 2007.
Byrn et al., “Solid State analysis of the active pharmaceutical ingredient in drug products”, 2003, DDT, vol. 8, No. 19, 898-905.
Bicher, et al., Anti-Cancer Drugs, 4:141-148 (1993).
Brill, J. Am. Chem. Soc., 54:2484-2487 (1932).
Chini, et al., Tetr. Lett., 35(5): 761-764 (1994).
Goldstein, et al., J. Natl. Cancer Inst., 81:116-124 (1989).
Gottesman, Ann. Rev. Med., 53:615-627 (2002).
Gottesman, et al., Nature Rev. Cancer, 2:48-58 (2002).
Hamel, et al., J. Biol. Chem., 259(4):2501-2508 (1984).
Hamel, Med. Res. Rev., 16:207-231 (1996).
Holmes, et al., J. Natl. Cancer Inst., 83(24):1797-1805 (1991).
Holton, et al., J. Am. Chem. Soc., 116(4):1597-1600 (1994).
Jones, et al., J. Chem. Soc. (B), pp. 1300-1315 (1971).
Jordan, et al., Cancer Res., 56:816-825 (1996).
Koepke, et al., J. Org. Chem., 44(15):2718-2722 (1979).
Kohn, et al., Natl. Cancer Inst., 86(1):18-24 (1994).
Kumar, J. Biol. Chem., 256(20):10435-10441 (1981).
Li, et al., Science & Medicine, Jan./Feb., pp. 38-47 (1999).
Loganzo, et al., Cancer Res. 63:1838-1845 (2003).
McGrath, et al., Biochem. Biophys. Res. Commun., 145(3):1171-1176 (1987).
McGuire, et al., Ann. Int. Med., 111(4):273-279 (1989).
Monteil, et al., J. Organomet Chem, 480:177-184 (1994).
Nicolaou, et al., Nature, 367:630-634 (1994).
Oka, et al., Tetrahedron, 54:1-20 (1998).
Rabindran, et al., Cancer Res., 58:5850-5858 (1998).
Rowinsky, et al., “Antimicrotubule Agents”,Cancer: Principles and Practice of Oncology, Chapter 19, Section 7, pp. 431-452 (2001).
Rowinsky, et al., Natl. Cancer Inst., 82(15):1247-1259 (1990).
Schiff, et al., Nature, 277-665-667 (1979).
Shen, et al., J. Boil. Chem., 261(17):7762-7770 (1986).
Wani, et al., J. Am. Chem. Soc., 93:2325-2327 (1971).
International Search Report and Written Opinion issued in PCT/US2007/011817, dated Dec. 13, 2007.
Blum David M.
Ku Mannching Sherry
Qi Fang Fang
Wu Yanzhong
Murray Jeffrey H
Wilmer Cutler Pickering Hale and Dorr LLP
Wilson James O
Wyeth Holdings Corporation
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