Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2007-10-02
2007-10-02
Aulakh, Charanjit S. (Department: 1625)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C514S089000
Reexamination Certificate
active
10531877
ABSTRACT:
The present invention relates to a crystalline, hydrated form of the sodium salt of 3-pyridyl-1-hydroxyethylidene-1,1-bisphosphonic acid. The hydrate contains from 6.4 up to 22 weight % of sodium and 15 up to 23 weight % of crystalline water if the sodium content is lower than 7.5 weight %, based on the whole molecule, or 4.5 up to 18 weight % of crystalline water if the sodium content is equal to or higher than 13 weight %, based on the anhydrous substance. Due to stability in humid environments, the hydrate is useful as an active substance for the treatment of diseases associated with bone resorption disorders.
REFERENCES:
patent: 2006/0148762 (2006-07-01), Richter et al.
patent: 01/56983 (2001-08-01), None
patent: 03/086355 (2003-10-01), None
Gossman, William L. et al.: “Three hydrates of the bisphosphonate risedronate, consisting of one molecular and two ionic structures”, Acta Crystallographica Section C, vol. C59, pp. m33-m36, Jan. 11, 2003.
Kushida, K.: “Sodium risedronate hydrate”, Rinsho To Yakubutsu Chiryo, vol. 21, No. 10, pp. 1040-1041, 2002. XP001157194.
Redman-Furey, Nancy L. et al.: “Thermoanalytical Characterization of the Hydration States of Risedronate”, Proceedings of the NATAS Annual Conference on Thermal Analysis and Applications, No. 30th, pp. 733-738, Sep. 21-22, 2002. XP009024613.
U.S. Appl. No. 10/590,694, filed Aug. 25, 2006, Richter et al.
Jirman Josef
Richter Jindrich
Aulakh Charanjit S.
Oblon & Spivak, McClelland, Maier & Neustadt P.C.
Zentiva A.S.
LandOfFree
Crystalline form of the sodium salt of... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Crystalline form of the sodium salt of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Crystalline form of the sodium salt of... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3845310