Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Web – sheet or filament bases; compositions of bandages; or...
Patent
1997-11-10
1999-07-27
Webman, Edward J.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Web, sheet or filament bases; compositions of bandages; or...
424448, 424469, 514182, 552625, A61K 970, A61K 926, A61K 3156
Patent
active
059286660
ABSTRACT:
The present invention is directed to a stable crystalline form of estradiol suitable for incorporation into pharmaceutical formulations. The invention further provides methods of preparing said crystalline form of estradiol. The invention further provides pharmaceutical formulations comprising said crystalline form of estradiol. The invention further provides a method of treatment of an individual in need of such administration by the transdermal administration of estradiol from a polymeric matrix comprising the crystal structure of estradiol of the present invention.
REFERENCES:
patent: 5827245 (1998-10-01), Horstmann et al.
Farinas Kathleen C.
Jayalakshmi Yalia
Lee Susanne M.
Soni Pravin L.
Cygnus Inc.
Horne Angela P.
McClung Barbara G.
Webman Edward J.
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