Crystalline form of a cephalosporin antibiotic

Details Crystalline form of a cephalosporin antibiotic Crystalline form of a cephalosporin antibiotic

1995-06-07

1996-12-31

Ford, John M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

540215, C07D50132

Patent

active

055895930

ABSTRACT:
The preparation of a novel crystalline cefaclor and the conversion of such a product to cefaclor monohydrate are described. The new intermediate cefaclor is a particular crystalline form and possesses the same antibiotic properties as cefaclor monohydrate.

REFERENCES:
patent: 3925372 (1975-12-01), Chauvette
patent: 4898938 (1990-02-01), Manuli
patent: 5142042 (1992-08-01), Chang et al.
patent: 5409918 (1995-04-01), Adam et al.
Journal of Medicinal Chemistry vol. 18, No. 14, Apr. 1975 Washington pp. 403-408.
Lorenz, Analytical Profile of Drug Substances, pp. 108-123 (1980) Academic Press.

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