Crystalline form of a biphenyl compound

Details Crystalline form of a biphenyl compound Crystalline form of a biphenyl compound

2008-01-22

2008-01-22

Seaman, D. Margaret (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C546S224000, C546S304000, C546S312000

Reexamination Certificate

active

07320990

ABSTRACT:
The invention provides a crystalline naphthalene-1,5-disulfonic acid salt of biphenyl-2-ylcarbamic acid 1-{9-[(R)-2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydro-quinolin-5 -yl)ethylamino]nonyl}piperidin-4-yl ester or a solvate thereof. This invention also provides pharmaceutical compositions comprising such a salt or prepared using such a salt; processes and intermediates for preparing such a salt; and methods of using such a salt to treat a pulmonary disorder.

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“Aclatonium Napadisilate,” Drugs of the Future, 7(4), pp. 227-228 (1982).

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