Crystalline fluoroquinolone arginine salt form

Details Crystalline fluoroquinolone arginine salt form Crystalline fluoroquinolone arginine salt form

2006-11-07

2006-11-07

Seaman, D. Margaret (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C546S094000

Reexamination Certificate

active

07132541

ABSTRACT:
The invention relates to the new arginine salt forms of RS-(±)-9-fluoro-6,7-dihydro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acid, S-(−)-9-fluoro-6,7-dihydro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acid, R-(+)-9-fluoro-6,7-dihydro-8-(4-hydroxypiperidin-1-yl)-5-methyl-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acid, a process for their preparation and pharmaceutical formulations which comprise those arginine salt forms as the active ingredient for its use in treating microbial infections.

REFERENCES:
patent: 3924042 (1975-12-01), Gerster et al.
patent: 3984403 (1976-10-01), Fujisawa et al.
patent: 3985882 (1976-10-01), Gerster et al.
patent: 4051247 (1977-09-01), Schuppan et al.
patent: 4382892 (1983-05-01), Hayakawa et al.
patent: 4399134 (1983-08-01), Ishikawa et al.
patent: 4404207 (1983-09-01), Stern et al.
patent: 4416884 (1983-11-01), Ishikawa et al.
patent: 4443447 (1984-04-01), Gerster et al.
patent: 4472406 (1984-09-01), Gerster et al.
patent: 4472407 (1984-09-01), Stern et al.
patent: 4535161 (1985-08-01), Hayakawa et al.
patent: 4552879 (1985-11-01), Ishikawa et al.
patent: 4594347 (1986-06-01), Ishikawa et al.
patent: 4599418 (1986-07-01), Irikura et al.
patent: 4638067 (1987-01-01), Culbertson et al.
patent: 4642355 (1987-02-01), Nakamura et al.
patent: 4665079 (1987-05-01), Culbertson et al.
patent: 4777175 (1988-10-01), Culbertson et al.
patent: 4822801 (1989-04-01), Domagala et al.
patent: 4874764 (1989-10-01), Ueda et al.
patent: 4894458 (1990-01-01), Masuzawa et al.
patent: 4935420 (1990-06-01), Ueda et al.
patent: 5051509 (1991-09-01), Nagano et al.
patent: 5097032 (1992-03-01), Domagala et al.
patent: 5185337 (1993-02-01), Fujii et al.
patent: 5200558 (1993-04-01), Kwan
patent: 5607942 (1997-03-01), Petersen et al.
patent: 5639886 (1997-06-01), Zerbes et al.
patent: 5677316 (1997-10-01), Ao et al.
patent: 5859026 (1999-01-01), Ito et al.
patent: 5869661 (1999-02-01), Ochi et al.
patent: 5889009 (1999-03-01), Miyake et al.
patent: 6034100 (2000-03-01), Adachi et al.
patent: 6121285 (2000-09-01), Takemura et al.
patent: 6184388 (2001-02-01), Takemura et al.
patent: 6329391 (2001-12-01), Ledoussal et al.
patent: 6514986 (2003-02-01), de Souza et al.
patent: 6664267 (2003-12-01), de Souza et al.
patent: 6750224 (2004-06-01), Patel et al.
patent: 2002/0061908 (2002-05-01), de Souza et al.
patent: 2003/0207908 (2003-11-01), Patel et al.
patent: 0230295 (1987-07-01), None
patent: 0241206 (1987-10-01), None
patent: 0287951 (1988-10-01), None
patent: 0304087 (1989-02-01), None
patent: 0342675 (1989-11-01), None
patent: 0394553 (1990-10-01), None
patent: 0541086 (1993-05-01), None
patent: 0572259 (1993-12-01), None
patent: 0908181 (1999-04-01), None
patent: 0919553 (1999-06-01), None
patent: 57081486 (1982-05-01), None
patent: 57176987 (1982-10-01), None
patent: 58090511 (1983-05-01), None
patent: 63192753 (1988-08-01), None
patent: 02131483 (1990-05-01), None
patent: 02188570 (1990-07-01), None
patent: 02188589 (1990-07-01), None
patent: 05339238 (1993-12-01), None
patent: 9420105 (1994-09-01), None
patent: 9731000 (1997-08-01), None
patent: 9744034 (1997-11-01), None
patent: 9914214 (1999-03-01), None
patent: 9926940 (1999-06-01), None
patent: 0018404 (2000-04-01), None
patent: 0068229 (2000-11-01), None
patent: 0185095 (2001-11-01), None
patent: 0185728 (2001-11-01), None
patent: 0209758 (2002-02-01), None
Mergler et al. Proceedings of the 12thAmerican Peptide Symposium. Reference cited on p. 2 pf EPA 0953577.
Alsina, et al.Tetrahedon Letters,v38 n5, (1997) 883-886.
Edwards et al.J. Med. Chem.,v37 n22 (1994) 3749-3757.
Oizumi et al.J. Infec. Chemotherapy,v7 (2001) 191-194.
Haustein et al.J. of Dermatological Treatment,v8 (1997) 87-92.
Bundgaard, H.Design of Prodrugs. (1985) p. 1-3.
Hashimoto et al.Chem. Pharm. Bull.V44, n4 (1996) p. 642-645.
Irish, D. et al.J. of Hospital Infection,v39 (1998) p. 19-26.
Kido, M. et al.Chem. Pharm. Bull.V42, n4 (1994) p. 872-876.
Sloan et al.Physics and Chemistry of the Organic Solid State,eds. D. Fox, Labes and Weissberer, Interscience Publishers, (1963) 179-182.
Takahashi et al.Arzheim-Forsc/Drug Res.,45(1), Nr.2 (1995), 199-197.
Morita, S. et al.Tetrahedoni: Assymetry,v6, n1 (1995) p. 245-254.
Morita, S. et al.Chem. Pharm. Bull.,38(7) (1990) 2027-2029.
Ishikawa et al.Chem. Pharm. Bull.,37(8) (1989) 2103-2108.
English translation of Yamada, H. et al.Iyahukin Kenkyu,v31, n8 (2000) p. 519-524.
English translation of Yamada, H. et al.Iyahukin Kenkyu,v31, n8 (2000) p. 525-528.
Berge et al.J. of Pharmaceutical Sciences,66(1) (1977) 1-19.
Abstract of Koike, M. et al.Iyakuhin Kenkyu,v21, n5 (1990) p. 998-1021.
Abstract of Koike, M. et al.Iyakuhin Kenkyu,v21, n5 (1990) p. 1022-1033.
Abstract of Fujita, S. et al.Iyakuhin Kenkyu,v21, n6 (1990) p. 1156-1176.
Abstract of Koike, M. et al.Yakubutsu Dotai,v5, n2 (1990) p. 199-208.
Abstract of Yasuo, A.. et al.Yakuri to Chiryo,v18, n4 (1990) p. 1717-1730.
Abstract of Hayakawa, R. et al.Hifu,v32, n2 (1990) p. 217-230.
Abstract of Asada, Y. et al.Yakuri to Chiryo,v18, n4 (1990) p. 1717-1730.
Abstract of Awogi, T. et al.Iyakuhin Kenkyu,v21, n4 (1990) p. 626-635.
Abstract of Matsuzawa, A. et al.Iyakuhin Kenkyu,v21, n4 (1990) p. 636-646.
Abstract of Nagao T. et al.Iyakuhin Kenkyu,v21, n4 (1990) p. 647-662.
Abstract of Matsuzawa, A. et al.Iyakuhin Kenkyu,v21, n4 (1990) p. 633-670.
Abstract of Hashimoto, K.. et al.Iyakuhin Kenkyu,v21, n4 (1990) p. 670-677.
Abstract of Furukawa, M. et al.Iyakuhin Kenkyu,v21, n5 (1990) p. 989-997.
Abstract of Kojima, K. et al.Iyakuhin Kenkyu,v21, n5 (1990) p. 1034-1052.
Abstract of Nakagiri, N. et al.Iyakuhin Kenkyu,v21, n6 (1990) p. 1144-1155.
Abstract of Aoki, M. et al.Iyakuhin Kenkyu,v21, n6 (1990) p. 1177-1202.
Abstract of Matsuzawa, A. et al.Iyakuhin Kenkyu,v22, n1 (1990) p. 61-76.
Abstract of Kurokawa I. et al.J. Am. Acad. Dermatol.,v25, n4 (1991) p. 674-681.
Abstract of Bojar, R. et al.J. of Investigative Dermatology,v103, n3 (1994) p. 405.
Abstract of Haustein, U.F. et al.J. of Dermatological Treatment,v8, n2 (1997) p. 87-92.
Abstract of Smith, C.M. et al.J. of Investigative Dermatology,v108, n3 (1997) p. 123.
Abstract of Hayakawa, R. et al.Hifu,v40, n2 (1998) p. 165-171.
Fujio, N. et al.Yakuri to Chiryo,v26, n7 (1998) p. 1119-1132.
Kido, M. et al.Chem. Pharm. Bull.,v44, n2 (1996) p. 421-423.
Miller, M.A. et al.Infection Control and Hospital Epidemiology,v17, n12 (1995) p. 811-813.
Nishijima, S. et al.The Journal of Int'l Medical Research,v23, (1995) p. 328-334.
Nishijima, S. et al.Journal of Dermatology, v22, (1995) p. 153-155.
Nishijima, S. et al.The Journal of Int'l Medical Research,v24, (1996) p. 12-16.
Nishijima, S. et al.Journal of Dermatology,v21, (1994) p. 233-238.
Udo, E. E. et al.J. of Hospital Infection,v26, (1994) p. 157-165.
Abstract of Kurokawa, I. et al.European J. of Dermatology,v9, n1 (1999) p. 25-28.
Abstract of Komagata. et al.Japanese Journal of Antibiotics,v51, n2 (1998) p. 130-136.
Abstract of Gollnick, H. et al.Dermatology,v196, n1(1998) p. 119-125.
Abstract of Nishijima, S. et al.J. of Int'l Medical Research, v25, n4 (1997) p. 210-213.
Abstract of Nishijima, S. et al.J. of In'tl Medical Research, v24, n6 (1996) p. 473-477.
Abstract of Akamatsu, H. et al.J. of Int'l Medical Research,v23, n1 (1995) p. 19-26.
Abstract of Takahashi, N. et al.Arzneimittel-Forschung, v45, n2 (1995) p. 195-.
Abstract of Takahashi, N. et al.Arzneimittal-Forschung,v44, n11 (1994) 1p. 265-1268.
Abstract of Patel, M.V. 39thICAAC at San Diego Poster No. F0558 (Sep. 26-29, 1999).
Chemical Abstract: Doc. No. 123:334723 Vogt, K. et al.Drugs,v49, Suppl.2 (1995).
Chemical Abstract: Doc. No. 123:334716 Nishijima et al.Drugs,v49, Suppl.2 (1995).
Chemical Abstract: Doc. No. 124:21098 Bojar, R.A. et al.Drugs,v49, Suppl.2 (1995).
Chemical Abstract: Doc. No. 122:213914,Tetrahedon: Asymmetry,v6, No. 1 (1995).
Chemical Abstract: Doc. No. 119:4810 Vogt, K. et al.Eur. J. Clin. Microbiol. Infect.
Chemical Abstract: Doc. No. 113:2131188 Morita, S. et al.Chem. Pharm. Bull.v38, n7.
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