Crystalline dihydrate of a cephalosporin salt

Details Crystalline dihydrate of a cephalosporin salt Crystalline dihydrate of a cephalosporin salt

1993-05-28

1995-02-21

Rizzo, Nicholas

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D50146

Patent

active

053917294

ABSTRACT:
The present invention relates to a new crystalline dihydrochloride dihydrate salt of the cephalosporin antibiotic, cefepime. In particular, this invention provides a temperature and moisture stable crystalline dihydrochloride dihydrate form of cefepime having enhanced stability and a specific x-ray powder diffraction pattern as described herein.

REFERENCES:
patent: 4406899 (1983-09-01), Aburaki et al.
patent: 4910301 (1990-03-01), Kaplan et al.
patent: 4994451 (1991-02-01), Kaplan et al.

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