Crystalline cephalosporin compounds

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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Details

Other Related Categories

C07D50146, A61K 31545

Type

Patent

Status

active

Patent number

050683225

Description

ABSTRACT:
The present invention relates to stable crystalline (6R,7R)-7-(Z)-2-(2-aminothiazol-4-yl)-2-(1-carboxy-1-methylethoxylimino)ac etamido]-3-(5,6-dihydroxy-2-methyl-2-isoindolinium)methyl-3-cephem-4-carbox ylate sulfate or its hydrate, a process for production of the compound and (6R,7R)-7-7-[(Z)-2-(2-aminothiazol-4-yl)-2-(1-carboxy-1-methylethoxyimino) acetamido]-3-(5,6-dihydroxy-2-methyl-2-isoindolinium)methyl-3-cephem-4-carb oxylate hydrochloride or its hydrate which is a starting material useful for the production of the desired compound of the present invention.

REFERENCES:
patent: 4677100 (1987-06-01), Nakagawa et al.

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