Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1990-05-14
1991-11-26
Rizzo, Nicholas S.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C07D50146, A61K 31545
Patent
active
050683225
ABSTRACT:
The present invention relates to stable crystalline (6R,7R)-7-(Z)-2-(2-aminothiazol-4-yl)-2-(1-carboxy-1-methylethoxylimino)ac etamido]-3-(5,6-dihydroxy-2-methyl-2-isoindolinium)methyl-3-cephem-4-carbox ylate sulfate or its hydrate, a process for production of the compound and (6R,7R)-7-7-[(Z)-2-(2-aminothiazol-4-yl)-2-(1-carboxy-1-methylethoxyimino) acetamido]-3-(5,6-dihydroxy-2-methyl-2-isoindolinium)methyl-3-cephem-4-carb oxylate hydrochloride or its hydrate which is a starting material useful for the production of the desired compound of the present invention.
REFERENCES:
patent: 4677100 (1987-06-01), Nakagawa et al.
Mano Eiichi
Nakagawa Susumu
Nakano Fumio
Ushijima Ryosuke
Yamada Koji
Banyu Pharmaceutical Co. Ltd.
Rizzo Nicholas S.
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