Crystalline anhydrous and monohydrate benzoate salts of...

Details Crystalline anhydrous and monohydrate benzoate salts of... Crystalline anhydrous and monohydrate benzoate salts of...

2006-05-02

2006-05-02

Saeed, Kamal A. (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

07038061

ABSTRACT:
A process for preparing an anhydrous benzoate salt in crystalline form having the formula I:and the corresponding benzoate monohydrate in crystalline form. The benzoate salts and pharmaceutical compositions thereof are selective kappa-receptor agonists, and are useful as analgesics, anesthetics, anti-inflammatory or neuroprotective agents, or in the treatment of arthritis, stroke or functional bowel disease.

REFERENCES:
patent: 6201007 (2001-03-01), Ito et al.
patent: 6294557 (2001-09-01), Ito et al.
patent: 02088082 (2002-11-01), None
Search Report, PCT/IB 03/00560, Apr. 10, 2003.

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