Crystalline ammonium N-acetyl-L-cysteinate and mucolytic process

Details Crystalline ammonium N-acetyl-L-cysteinate and mucolytic process Crystalline ammonium N-acetyl-L-cysteinate and mucolytic process

1972-02-03

1976-06-22

Evans, Joseph E.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424315, C07C10104

Patent

active

039651673

ABSTRACT:
The ammonium salt of N-acetyl-L-cysteine is a relatively non-hygroscopic crystalline solid which renders it particularly useful for administration by insufflation in the treatment of bronchopulmonary disease. It is of use in a mucolytic process wherein bronchopulmonary mucus is contacted with solid ammonium N-acetyl-L-cysteinate utilizing only the energy of the inspiratory action of the inhaler.

REFERENCES:
patent: 3091569 (1963-05-01), Sheffner
patent: 3647834 (1972-03-01), Martin
Martin et al., J. Med. Chem., 11, 625, 1968.

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