Crystalline amifostine compositions

Details Crystalline amifostine compositions Crystalline amifostine compositions

1995-02-16

1997-01-07

Richter, Johann

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

558166, A61K 3166, C07F 9165

Patent

active

055917313

ABSTRACT:
The present invention relates to a sterile, stable vacuum dried crystalline amifostine composition and, optionally, pharmaceutically acceptable excipient(s). Typically, the crystalline compositions of the present invention exhibit enhanced stability at temperatures ranging from about 4.degree. C. to about ambient temperature for a period of at least 2 years relative to existing solid vacuum dried amorphous amifostine preparations. The reconstituted compositions of the present invention are suitable for administration to humans as a radio- or chemoprotecting agent.

REFERENCES:
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