Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2011-06-07
2011-06-07
Chu, Yong (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S422000, C514S424000, C548S248000, C548S518000, C548S543000
Reexamination Certificate
active
07956078
ABSTRACT:
The invention relates to a method of developing a main proteinase SARS inhibitor. Human coronaviruses are major causes of upper respiratory tract illnesses in humans, in particular, the common cold. Recent investigations have shown that a novel coronavirus causes the Severe Acute Respiratory Syndrome (SARS), a disease that is characterized by high fever, malaise, rigor, headache, non-productive cough or dyspnea, which is rapidly spreading. Within the scope of the invention, based on the structural analysis of the binding mode of the SARS Mproenzyme, a group of prototype inhibitors is provided that acts as suitable drugs targeting a majority of viral infections of the respiratory tract, including SARS.
REFERENCES:
patent: 6906198 (2005-06-01), Dragovich et al.
Matthews et al., Proceedings of the National Academy of Sciences of the United States of America,1999, 96(20), p. 11000-11007.
Shie et al., Bioorganic & Medicinal Chemistry, 2005, vol. 13, p. 5240-5252.
Patani et al., Chem. Rev., 1996, vol. 96, p. 3147-3176.
Anand Kanchan
Hilgenfeld Rolf
Mesters Jeroen R.
Wadhwani Parvesh
Ziebuhr John
Chu Yong
Diederiks & Whitelaw PLC
Universitat zu Luebeck
LandOfFree
Crystal structure of human coronavirus 229E main proteinase... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Crystal structure of human coronavirus 229E main proteinase..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Crystal structure of human coronavirus 229E main proteinase... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2663330