Crystal structure of G-quadruplex containing a potassium ion

Details Crystal structure of G-quadruplex containing a potassium ion Crystal structure of G-quadruplex containing a potassium ion

2007-12-25

2007-12-25

Steadman, David J. (Department: 1656)

Chemistry: analytical and immunological testing

Process or composition for determination of physical state...

Of crystal or crystalline material

C514S297000, C536S023500

Reexamination Certificate

active

10405085

ABSTRACT:
The present invention relates to a crystal structure of G-quadruplexes and its use. The invention provides a crystal of an intramolecular G-quadruplex structure having a hexagonal space group P6, and unit cell dimensions a=b=56.7 and c=42.1; α=β=90°, γ=120° and a crystal of G-quadruplex having the three dimensional atomic coordinates of Table 1 or Table 2. These structures may be used in a computer-based method for the analysis of the interaction of a molecular structure with a G-quadruplex.

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