Crystal of the N-terminal domain of a STAT protein and methods o

Details Crystal of the N-terminal domain of a STAT protein and methods o Crystal of the N-terminal domain of a STAT protein and methods o

1998-01-23

2000-07-11

Nashed, Nashaat

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

530421, 435 691, 436 86, 702 19, C07K 100

Patent

active

060874783

ABSTRACT:
The present invention provides a crystal containing the N-terminal domain of a STAT protein that is of sufficient quality to perform X-ray crystallographic studies. Methods of preparing the crystals are include in the invention. The present invention further discloses the three-dimensional structure of the crystal. The present invention also provides methods of using the structural information in drug discovery and drug development.

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