Crystal of hydroxynorephedrin derivative hydrochloride...

Details Crystal of hydroxynorephedrin derivative hydrochloride... Crystal of hydroxynorephedrin derivative hydrochloride...

2011-08-23

2011-08-23

Padmanabhan, Sreeni (Department: 1627)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

C560S042000

Reexamination Certificate

active

08003694

ABSTRACT:
The present invention provides ethyl (−)-2-[4-[2-[[1S,2R]-2-hydroxy-2-(4-hydroxyphenyl)-1-methylethyl]amino]ethyl]-2,5-dimethylphenoxyacetate hydrochloride ¼ hydrate or a crystal thereof which can be determined by characteristic diffraction peaks of the powder X-ray diffraction, thermogravimetry-differential thermal analysis or the like, and obtained by manufacturing ethyl (−)-2-[4-[2-[[1S,2R]-2-hydroxy-2-(4-hydroxyphenyl)-1-methyl-ethyl]amino]ethyl]-2,5-dimethylphenoxyacetate by a specific method.

REFERENCES:
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patent: 2006/0135605 (2006-06-01), Tanaka et al.
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patent: 2002-338513 (2002-11-01), None
patent: 03/024916 (2003-03-01), None
Supplementary European Search Report dated Jun. 30, 2010.

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