Crystal of bicalutamide and production method thereof

Details Crystal of bicalutamide and production method thereof Crystal of bicalutamide and production method thereof

2006-11-07

2006-11-07

Saeed, Kamal A. (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitriles

C558S414000

Reexamination Certificate

active

07132560

ABSTRACT:
The present invention relates to a crystal of bicalutamide having a defined form, as well as economical and industrially practical production methods of bicalutamide and a crystal thereof, which are superior in environmental benignity and safety.Accordingly, the present invention provides a production method of bicalutamide represented by the formula (I):which includes at least a step of reacting a compound represented by the formula (3):with an oxidizing agent, a production method of a crystal of bicalutamide, as well as a crystal form of bicalutamide as defined by X-ray diffraction (XRD) or solid13C NMR measurement.

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