Crystal modifications of (+)-catechin and pharmaceutical prepara

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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549399, 514894, A61K 3135, C07D31162

Patent

active

045158045

ABSTRACT:
Novel crystal modifications of (+)-catechin monohydrate and of (+)-catechin anhydrate more suitable for pharmaceutical preparations for reasons of higher stability against moisture and/or light and distinguished from hitherto known modifications by unique X-ray diffraction spectra are produced by specific recrystallization and/or crystal rearrangement processes and pharmaceutical preparations comprising the novel crystal forms.

REFERENCES:
The Merck Index, 9th ed., 1976, p. 1901.
Blum et al., Lancet, pp. 1153-1155 (1977).
Reina et al., Fortschr. Med, 96, 75 (1978).

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