Crystal harvest from fermentation broth

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Using a micro-organism to make a protein or polypeptide

Reexamination Certificate

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C435S272000

Reexamination Certificate

active

07118891

ABSTRACT:
A method for producing a crystalline and/or amorphous metabolite suspension from a fermentation broth comprising treating the fermentation broth with one or more coagulants and/or one or more flocculants; and separating the biomass of the fermentation broth from the coagulated and/or flocculated fermentation broth by use of a separation equipment, whereby a crystalline and/or amorphous metabolite suspension is obtained.

REFERENCES:
patent: 4659667 (1987-04-01), Brewer et al.
patent: 5445949 (1995-08-01), Koster et al.
patent: 0 574 050 (1993-12-01), None
patent: 2 679 235 (1993-01-01), None
patent: WO 95/01989 (1995-01-01), None
patent: WO 96/38469 (1996-12-01), None
Bajpal et al., Biotechnecology Techniques, vol. 4, No. 4., pp. 227-232 (1990).

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