Crystal growth devices and systems, and methods for using same

Chemical apparatus and process disinfecting – deodorizing – preser – Physical type apparatus – Crystallizer

Reexamination Certificate

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C117S068000, C117S069000, C117S925000, C117S927000

Reexamination Certificate

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10827917

ABSTRACT:
High throughput screening of crystallization of a target material is accomplished by simultaneously introducing a solution of the target material into a plurality of chambers of a microfabricated fluidic device. The microfabricated fluidic device is then manipulated to vary the solution condition in the chambers, thereby simultaneously providing a large number of crystallization environments. Control over changed solution conditions may result from a variety of techniques, including but not limited to metering volumes of crystallizing agent into the chamber by volume exclusion, by entrapment of volumes of crystallizing agent determined by the dimensions of the microfabricated structure, or by cross-channel injection of sample and crystallizing agent into an array of junctions defined by intersecting orthogonal flow channels.

REFERENCES:
patent: 3570515 (1971-03-01), Kinner
patent: 3747628 (1973-07-01), Holster et al.
patent: 4046159 (1977-09-01), Pegourie
patent: 4119368 (1978-10-01), Yamazaki
patent: 4153855 (1979-05-01), Feingold
patent: 4245673 (1981-01-01), Bouteille et al.
patent: 4434704 (1984-03-01), Surjaatmadja
patent: 4898582 (1990-02-01), Faste
patent: 4948564 (1990-08-01), Lyman et al.
patent: 4992312 (1991-02-01), Frisch
patent: 5085562 (1992-02-01), Van Lintel
patent: 5088515 (1992-02-01), Kamen
patent: 5096388 (1992-03-01), Weinberg
patent: 5126115 (1992-06-01), Fujita et al.
patent: 5164558 (1992-11-01), Huff et al.
patent: 5171132 (1992-12-01), Miyazaki et al.
patent: 5224843 (1993-07-01), Van Lintel
patent: 5259737 (1993-11-01), Kamisuki et al.
patent: 5265327 (1993-11-01), Faris et al.
patent: 5290240 (1994-03-01), Horres, Jr.
patent: 5336062 (1994-08-01), Richter
patent: 5346372 (1994-09-01), Naruse et al.
patent: 5375979 (1994-12-01), Trah
patent: 5376252 (1994-12-01), Ekstrom et al.
patent: 5400741 (1995-03-01), DeTitta et al.
patent: 5423287 (1995-06-01), Usami et al.
patent: 5529465 (1996-06-01), Zengerle et al.
patent: 5593130 (1997-01-01), Hansson et al.
patent: 5637469 (1997-06-01), Wilding et al.
patent: 5642015 (1997-06-01), Whitehead et al.
patent: 5659171 (1997-08-01), Young et al.
patent: 5660370 (1997-08-01), Webster
patent: 5681024 (1997-10-01), Lisec et al.
patent: 5705018 (1998-01-01), Hartley
patent: 5759014 (1998-06-01), Van Lintel
patent: 5775371 (1998-07-01), Pan et al.
patent: 5788468 (1998-08-01), Dewa et al.
patent: 5836750 (1998-11-01), Cabuz
patent: 5842787 (1998-12-01), Kopf-Sill et al.
patent: 5875817 (1999-03-01), Carter
patent: 5876187 (1999-03-01), Afromowitz et al.
patent: 5876675 (1999-03-01), Kennedy et al.
patent: 5885470 (1999-03-01), Parce et al.
patent: 5932100 (1999-08-01), Yager et al.
patent: 5932799 (1999-08-01), Moles
patent: 5942443 (1999-08-01), Parce et al.
patent: 5958694 (1999-09-01), Nikiforov
patent: 6007309 (1999-12-01), Hartley
patent: 6043080 (2000-03-01), Lipshutz et al.
patent: 6123769 (2000-09-01), Sanjoh
patent: 6155282 (2000-12-01), Zachary et al.
patent: 6165694 (2000-12-01), Liu
patent: 6174365 (2001-01-01), Sanjoh
patent: 6174675 (2001-01-01), Chow et al.
patent: 6296673 (2001-10-01), Santarsiero et al.
patent: 6345502 (2002-02-01), Tai et al.
patent: 6409832 (2002-06-01), Weigl et al.
patent: 6767706 (2004-07-01), Quake et al.
patent: 2001/0027745 (2001-10-01), Weigl et al.
patent: 2001/0041357 (2001-11-01), Fouillet et al.
patent: 2002/0037499 (2002-03-01), Quake et al.
patent: 2002/0145231 (2002-10-01), Hansen et al.
patent: 2002/0195050 (2002-12-01), David
patent: 2003/0026740 (2003-02-01), Staats
patent: 2003/0027225 (2003-02-01), Wada et al.
patent: 2003/0061687 (2003-04-01), Hansen et al.
patent: 2003/0096310 (2003-05-01), Hansen et al.
patent: 2004/0115731 (2004-06-01), Hansen et al.
patent: 2005/0062196 (2005-03-01), Hansen et al.
patent: 2005/0205005 (2005-09-01), Hansen et al.
patent: 2005/0229839 (2005-10-01), Quake et al.
patent: 592 094 (1994-04-01), None
patent: 703 364 (1996-03-01), None
patent: 706 004 (1996-04-01), None
patent: 779 436 (1997-06-01), None
patent: 829 360 (1998-03-01), None
patent: 845 603 (1998-06-01), None
patent: 999 055 (2000-10-01), None
patent: 2 155 152 (1985-09-01), None
patent: 2 308 460 (1997-06-01), None
patent: 98/07069 (1998-02-01), None
patent: WO99/00655 (1999-01-01), None
patent: WO99/04361 (1999-01-01), None
patent: WO99/17093 (1999-04-01), None
patent: WO99/52633 (1999-10-01), None
patent: WO 00/00678 (2000-01-01), None
patent: WO 00/43748 (2000-07-01), None
patent: WO 00/60345 (2000-10-01), None
patent: WO 01/09595 (2001-02-01), None
patent: WO 01/09595 (2001-02-01), None
“Biochips,” Nature Biotechnology, vol. 18, Supplement 2000, pp. IT43-IT44, 2000.
“Last Chance For Micrcomachines,” The Economist Technology Quarterly, 8 pages, Dec. 7, 2000.
“The Liver Chip,” Technology Review, pp. 64-67, Mar. 2003.
Abola, Enrique et al., “Automation Of X-Ray Crystallography,” Nature Structural Biology, Structural Genomics Supplement, pp. 973-977, Nov. 2000.
Andersen, Gregers Rom et al., “A Spreadsheet Approach To Automated Protein Crystallization,” Journal of Applied Crystallography, vol. 29, pp. 236-240, 1996.
Anderson, Rolfe C. et al., “Microfluidic Biochemical Analysis System,” Transducer '97, 1997 International Conference on Solid-State Sensors and Actuators, Chicago, Illinois, pp. 477-480, Jun. 16-19, 1997.
Angell, James B. et al., “Silicon Micromechanical Devices,” Scientific American, pp. cover, 44-55, Apr. 1983.
Armani, Deniz et al., “Re-Configurable Fluid Circuits By PDMS Elastomer Micromachining,” IEEE Int. Conf. Micro Electro Mech. Syst. Tech. Digest, vol. 12, pp. 222-227, 1999.
Ballantyne, J. P. et al., “Selective Area Metallization By Electron-Beam Controlled Direct Metallic Deposition,” J. Vac. Sci. Technol., vol. 10, No. 6, pp. 1094-1097, Nov. 1973.
Belgrader, Phillip et al., “Rapid Pathogen Detection Using A Microchip PCR Array Instrument,” Clinical Chemistry, vol. 44, No. 10, pp. 2191-2194, 1998.
Berry, Michael B., “Protein Crystallization: Theory And Practice,” Excerpts from Doctoral Thesis, 36 pages, Sep. 17, 1995.
Black, Harvey, “Tiny Technology Promises Tremendous Profits,” The Scientist, vol. 15, No. 21, 4 pages, Oct. 29, 2001.
Bloomstein, T. M. et al., “Laser-Chemical Three-Dimensional Writing For Microelectromechanics And Application To Standard-Cell Microfluidics,” J. Vac. Sci. Technol. B, vol. 10, No. 6, pp. 2671-2674, Nov. 1992.
Bousse, Luc et al., “Electrokinetically Controlled Microfluidic Analysis Systems,” Annu. Rev. Biophys. Biomol. Struct., vol. 29, pp. 155-181, 2000.
Brush, Michael, “Automated Laboratories,” The Scientist, vol. 13, No. 4, 10 pages, Feb. 15, 1999.
Burbaum, Jonathan J. et al., “New Technologies For High-Throughput Screening,” Current Opinion in Chemical Biology, vol. 1, pp. 72-78, 1997.
Calkins, Kathryn, “Mycometrix: Rubber Chips,” BioCentury, 2 pages, Oct. 16, 2000.
Chang, Jun Keun et al., “Functional Integration Of Serial Dilution and Capillary Electrophoresis On A PDMS Microchip,” Biotechnology and Bioprocess Engineering, vol. 8, No. 4, pp. 233-239, 2003.
Chayen, Naomi E., “A Novel Technique To Control The Rate Of Vapour Diffusion, Giving Larger Protein Crystals,” Journal of Applied Crystallography, vol. 30, pp. 198-202, 1997.
Chayen, Naomi E. et al., “An Automated System For Micro-Batch Protein Crystallization And Screening,” J. Appl: Cryst., vol. 23, pp. 297-302, 1990.
Chayen, Naomi E., “Comparative Studies Of Protein Crystallization By Vapour-Diffusion And Microbatch Techniques,” Acta Cryst., vol. D54, pp. 8-15, 1998.
Chayen, Naomi E. et al., “Microbatch Crystallization Under Oil—A New Technique Allowing Many Small-Volume Crystallization Trials,” Journal of Crystal Growth, vol. 122, pp. 176-180, 1992.
Chayen, Naomi E. et al., “New Developments Of The IMPAX Small-Volume Automated Crystallizat

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