Crystal form I of clarithromycin

Details Crystal form I of clarithromycin Crystal form I of clarithromycin

1996-07-29

1999-01-12

Peselev, Elli

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 72, 536 185, 536127, A61K 3170, C07H 100, C07H 1708

Patent

active

058589864

ABSTRACT:
The present invention concerns the novel antiobiotic 6-O-methylerythromycin A crystal form I, a process for its preparation, pharmaceutical compositions comprising this compound and a method of use as a therapeutic agent.

REFERENCES:
patent: 4670549 (1987-06-01), Morimoto et al.
patent: 4672109 (1987-06-01), Wantanabe et al.
patent: 4990602 (1991-02-01), Morimoto et al.
Quantitative Structure-Activity Relationships In Drug Design, vol. 291 (1989), pp. 325-328, Kim et al., "Conformational Study of Erythromycin Analogues".
Acta Crystallographica, vol. c49, No. 5 (May 1993), pp. 1227-1230, Iwasaki et al., "Structure of 6-O-Methylerythromycin A (Clarithromycin)".

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