Crosslinked silane coating for medical devices

Details Crosslinked silane coating for medical devices Crosslinked silane coating for medical devices

2011-05-10

2011-05-10

Azpuru, Carlos A (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

C424S423000, C424S424000, C424S425000

Reexamination Certificate

active

07939095

ABSTRACT:
Coatings are provided in which surfaces may be activated by covalently bonding a combination ofsilane derivatives (A) to the metal surface, covalently bonding a lactone polymer (B) to the silane derivative by in situ ring opening polymerization, and depositing at least one layer of a polyester (C) on the bonded lactone polymer. Biologically active agents or therapeutic compounds may be deposited with any of the polyester layers. Such coated surfaces may be useful in medical devices, in particular stents.

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