Crosslinked hyaluronate gels, their use and method for producing

Details Crosslinked hyaluronate gels, their use and method for producing Crosslinked hyaluronate gels, their use and method for producing

1996-04-26

1998-07-21

Peselev, Elli

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 553, C07H 504

Patent

active

057836914

ABSTRACT:
The present invention relates to a crosslinked hyaluronic acid derivative in which the crosslinking has been achieved by means of reaction with a phosphorus-containing reagent, especially a derivative of an acid of phosphorus (V). The invention also relates to the methods of producing such a product as well as its use as a slow release depot for administration of hylaluronic acid or a medicament incorporated in the gel.

REFERENCES:
patent: 3422088 (1969-01-01), Tuschhoff
patent: 3555009 (1971-01-01), Suzuki
patent: 3936441 (1976-02-01), Holst et al.
patent: 4152170 (1979-05-01), Nagase
patent: 4605691 (1986-08-01), Balazs et al.
patent: 4716154 (1987-12-01), Malson et al.
patent: 4716224 (1987-12-01), Sakurai et al.
patent: 4957744 (1990-09-01), della Valle et al.
Balasz Chemical Abstracts vol. 98, No. 19, No 161088y, 1983.

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