Crosslinked anion exchange particles and method for producing th

Drug – bio-affecting and body treating compositions – Solid synthetic organic polymer as designated organic active... – Ion exchange resin

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

528272, 528288, 528299, 528302, 528303, 528397, 525437, 525445, 522 1, 5147723, 552548, A61K 31785

Patent

active

055002129

ABSTRACT:
New bile acid sequestrant polymer compositions and a process for preparing the polymers in particulate form, preferably in spherical form, are described. The polymer particles are prepared by crosslinking an amine-containing polymer with an amount of a polyfunctional amine-reactive compound sufficient to crosslink the polymer so that it is essentially water insoluble and has bile acid sequestering efficacy greater than that of cholestyramine, preferably greater than about three times the efficacy of cholestyramine. A preferred polymerization process revolves suspension polymerization of water-soluble amine-containing monomers, such as dialkylaminoalkyl (meth)acrylate esters and dialkylaminoalkyl (meth)acrylamides, in the presence of polyfunctional amine-reactive compounds, such as substituted dihaloalkanes. Pharmaceutical compositions containing the bile acid sequestrant polymer particles and a method for lowering blood cholesterol levels using the pharmaceutical compositions are also described.

REFERENCES:
patent: 3383281 (1968-05-01), Wolf et al.
patent: 3692895 (1972-09-01), Nelson et al.
patent: 4046750 (1977-09-01), Rembaum
patent: 5300288 (1994-04-01), Albright

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Crosslinked anion exchange particles and method for producing th does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Crosslinked anion exchange particles and method for producing th, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Crosslinked anion exchange particles and method for producing th will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1958004

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.